Monodisperse microbeads of hypercrosslinked polystyrene for liquid and supercritical fluid chromatography

Tsyurupa, M. P.; Blinnikova, Z. K.; Il’in, M. M.; Davankov, V. A.; Паренаго, О. О.; Покровский, О. И.; Usovich, O. I.

doi:10.1134/s0036024415110217

Cited by 10 publications

(11 citation statements)

References 13 publications

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“…However, the accuracy of the dynamic methods is largely dependent on the column packing with an adsorbent due to the hydrodynamic effects [ 26 ]. This means that these methods are not reliable in case of HCP studied in our work as we have earlier determined in our laboratory that the use of such materials in SCF leads to changes in the particle size caused by swelling and destruction of the column packing layer [ 27 ].…”

Section: Introductionmentioning

confidence: 91%

Adsorption of N,N,N′,N′-Tetraoctyl Diglycolamide on Hypercrosslinked Polysterene from a Supercritical Carbon Dioxide Medium

Kostenko

Паренаго

2021

Molecules

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The work considers for the first time the preparation of sorbents based on hypercrosslinked polysterene (HCP) and chelating agent N,N,N′,N′-tetraoctyldiglycolamide (TODGA) by impregnation in the supercritical (SC) CO2 medium. Such sorbents can be applied for further isolation and separation of lanthanides, actinides and other metals. They are usually prepared by impregnation in toxic organic solvents (e.g., methanol, dichloromethane). Our study shows that application of SC CO2 instead of organic solvents can significantly speed up the impregnation, perfom it in one stage and make the process more eco-friendly. At the same time, the obtained sorbents are close in their parameters to the classical ones. This article presents the results of measuring the TODGA adsorption isotherms on two HCP sorbents (MN202 and MN270) on a wide range of SC fluid parameters. Adsorption measurements were carried out using on-line supercritical fluid chromatography and gravimetry. Based on the sorption capacity parameter, MN202 sorbent was selected as the better carrier for TODGA. An impregnation temperature increase within the range 313–343 K in isochoric conditions (ρ = 0.780 g/mL) reduces the maximum of TODGA adsorption from ~0.68 mmol/g to ~0.49 mmol/g.

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Section: Introductionmentioning

confidence: 91%

Adsorption of N,N,N′,N′-Tetraoctyl Diglycolamide on Hypercrosslinked Polysterene from a Supercritical Carbon Dioxide Medium

Kostenko

Паренаго

2021

Molecules

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“…Monodisperse styrene-divinylbenzene copolymer microbeads were used as stationary phase for the separation of model compounds, that is, toluene and nitrophenol [220]. The stainless-steel analytical column was filled with a suspension of the polymer microbeads in acetone/water (1/2), and subsequently, the same mixture with microbeads was fed into the system via the slow increase in pressure [220]. The prepared column was tested using a mixture of toluene and nitrophenols in both LC and SFC conditions.…”

Section: Unconventional Stationary Phases In Sfcmentioning

confidence: 99%

Columns in analytical‐scale supercritical fluid chromatography: From traditional to unconventional chemistries

Plachká

Pilařová

Horáček

et al. 2023

J of Separation Science

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Within this review, we thoroughly explored supercritical fluid chromatography (SFC) columns used across > 3000 papers published from the first study carried out under SFC conditions in 1962 to the end of 2022. We focused on the open tubular capillary, packed capillary, and packed columns, their chemistries, dimensions, and trends in used stationary phases with correlation to their specific interactions, advantages, drawbacks, used instrumentation, and application field. Since the 1990s, packed columns with liquid chromatography and SFC‐dedicated stationary phases for chiral and achiral separation are predominantly used. These stationary phases are based on silica support modified with a wide range of chemical moieties. Moreover, numerous unconventional stationary phases were evaluated, including porous graphitic carbon, titania, zirconia, alumina, liquid crystals, and ionic liquids. The applications of unconventional stationary phases are described in detail as they bring essential findings required for further development of the supercritical fluid chromatography technique.

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Section: Wide Range Of Applications For Hyper-cross-linked Polymersmentioning

confidence: 99%

“…These HCPs were able to successfully separate many aromatic compounds, such as 2,4-dinitrophenol, phenol, p-nitrophenol, o-nitrophenol, dimethyl phthalate, diethyl phthalate, and di-n-propyl phthalate, among others. Tsyurupa et al 71 also used styrenebased HCPs, but based on divynilbenzene as a copolymer, to completely separate acetone, benzene, naphthalene, anthra-cene, toluene, p-nitrophenol, and 2,6-dinitrophenol. Using instead cholesteryl methacrylate together with other aromatic compounds, HCPs were successfully tested as capillary columns for the separation of alkylbenzenes, o-terphenyl/ triphenylene, parabens, and proteins.…”

Section: Hyper-cross-linked Polymersmentioning

confidence: 99%

Eco-Friendly Production of Hyper-Cross-Linked Polymers Using Mechanosynthesis and Bioresources: A Critical Review

Borrero-López

Celzard

Fierro

2022

ACS Sustainable Chem. Eng.

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Hyper-cross-linked polymers (HCPs) are receiving great attention due to their high specific surface areas, allowing them to offer high performances in many different applications. However, most of the time, their syntheses require hazardous and time-consuming protocols, making their implementation and scaling up difficult. To overcome this problem, a relatively old technology such as mechanosynthesis (MS) has gained renewed interest as a greener and faster technology to produce HCPs, which involves much lower energy consumption during the reaction process. In this perspective, the latest advances on the performances of HCPs based on MS protocols are compiled and analyzed, subdivided into those based on Friedel–Crafts alkylation, Scholl coupling reactions, and other less common procedures. An analysis of MS versus solvent-based protocols regarding the 12 principles of green chemistry is also reported, as well as a section including a summary of the most recent applications of HCPs. Finally, the use of biobased precursors for the formulation of HCPs is discussed, thus pooling knowledge for greener, faster, and more widely applicable future development of HCPs.

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Monodisperse microbeads of hypercrosslinked polystyrene for liquid and supercritical fluid chromatography

Cited by 10 publications

References 13 publications

Adsorption of N,N,N′,N′-Tetraoctyl Diglycolamide on Hypercrosslinked Polysterene from a Supercritical Carbon Dioxide Medium

Adsorption of N,N,N′,N′-Tetraoctyl Diglycolamide on Hypercrosslinked Polysterene from a Supercritical Carbon Dioxide Medium

Columns in analytical‐scale supercritical fluid chromatography: From traditional to unconventional chemistries

Eco-Friendly Production of Hyper-Cross-Linked Polymers Using Mechanosynthesis and Bioresources: A Critical Review

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