Mono‐, Bi‐ and Tridentate N‐Heterocyclic Carbene Ligands for the Preparation of Transition‐Metal‐Based Homogeneous Catalysts

Abstract

This microreview focuses on the preparation of homogeneous catalysts of group 8-11 metals containing Nheterocyclic carbene ligands. The current status of the design of mono-, bi-and tridentate NHC ligands is reviewed through the description of the authors' own work. The cata-

Intramolecular Oxidation of the Alcohol Functionalities in Hydroxyalkyl‐N‐Heterocyclic Carbene Complexes of Iridium and Rhodium

“…[14] Because we are interested in experimentally studying the reaction mechanisms that involve the oxidation of alcohols by Ir III complexes, we thought that using N-heterocyclic carbenes with alcohol substituents at the NHC wingtips might shed some light into the reaction pathways that govern the processes. The introduction of the alcohol functionality close to the active metal center might help produce the activation of the alcohol through a chelate-assisted process, and the transformed products are forced to remain attached to the metal, thus allowing for their complete characterization and facilitating the study of their reactivity through further subsequent reactions.…”

Enhanced cytotoxicity of silver complexes bearing bidentate N-heterocyclic carbene ligands

“…[1][2][3][4] To a much lesser extent they have been investigated in biomedical applications, showing promise as antimicrobial (silver-NHCs) and as antitumour agents. [5][6][7] The antimicrobial properties of silver are well established and have resulted in silver being incorporated into several materials such as wound dressings, creams, deodorants and even clothing.…”

Ligand Exchange at a Gold(I) Carbene Complex

“…N-heterocyclic carbenes (NHCs) have been in the focus of interest [1 -4] due to their application as organocatalysts [5,6] or as ligands in transition metal complexes [1 -4, 7, 8], many of which are active in various homogeneous catalytic reactions [9,10]. NHC complexes feature an impressive stability against air, heat and moisture.…”