Monkeypox Infection Causing Conjunctival Vesicles and Anterior Uveitis

Spectrum of ophthalmic manifestations in monkeypox virus infection worldwide: Systematic review and meta-analysis

“…Ophthalmic symptoms appeared 1 week after systemic vesicles. Carvalho (2023) [ 34 ] Brazil Case report 1 28 y, male PCR Hyperemia and vesicles in the bulbar conjunctiva. small keratic precipitates, +1 anterior chamber cells, and discrete cells in the anterior vitreous were observed.…”

“…Four case reports described anterior uveitis [ 34 , 36 , 42 , 43 ]. All had mild inflammation (0.5 or 1+ of cells) and were accompanied by corneal compromise.…”

“…All had mild inflammation (0.5 or 1+ of cells) and were accompanied by corneal compromise. Two had keratic precipitates [ 34 , 42 ], and one had keratitis with epithelial corneal ulcer and superior limbitis [ 43 ]. For more detailed information regarding the frequency of uveitis by type of study, see Table 2 .…”

“…Overall, the outcomes of most cases were positive, with the majority achieving full recovery and preserving a visual acuity of 20/25 or better [ 30 , 34 , 35 , 37 , 41 , 44 ]. However, serious complications were reported in some cases.…”

“… Doxycycline, fluconazole, acyclovir, Oral tecovirimat 600 mg twice a day for 14 days ciprofloxacin 3.5 mg/mL eye drop prophylactic acyclovir 400 mg five times a day for 5 days gatifloxacin 0.3% eye drop for 10 days. 15 days after starting tecovirimat Corneal scaring (20/100) Negative Carvalho (2023) [ 34 ] Hyperemia and vesicles in the bulbar conjunctiva. Small keratic precipitates, +1 anterior chamber cells, and discrete cells in the anterior vitreous were observed.…”