Monitoring of organochlorine pesticides in blood of women with uterine cervix cancer

Rodríguez, Ángel Gabriel Polanco; Lopez, Mario; Casillas, Tomas Angel DelValls; León, Jesús Alfredo Araujo; Mahjoub, Olfa; Prusty, Anjan Kumar

doi:10.1016/j.envpol.2016.10.068

Cited by 78 publications

(20 citation statements)

References 50 publications

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“…Studies also revealed a close relationship between pesticides and cancer development in both adults and children. The people closely associated with pesticide exposure were reported to be at a high-risk level for numerous malignancies, such as neuroblastoma, leukemia, soft tissue sarcoma, Burkitt lymphoma, non-Hodgkin lymphoma, Wilm's tumor, lung cancer, ovarian cancer, and rectum [262][263][264]. Several epidemiological and clinical studies have documented a relationship between pesticide toxicity and symptoms of bronchial hyper-reactivity and asthma.…”

Section: Effect Of Pesticides Toxicity On Human Healthmentioning

confidence: 99%

Heavy Metals and Pesticides Toxicity in Agricultural Soil and Plants: Ecological Risks and Human Health Implications

Alengebawy

Abdelkhalek

Qureshi

et al. 2021

Toxics

1,020

352

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Environmental problems have always received immense attention from scientists. Toxicants pollution is a critical environmental concern that has posed serious threats to human health and agricultural production. Heavy metals and pesticides are top of the list of environmental toxicants endangering nature. This review focuses on the toxic effect of heavy metals (cadmium (Cd), lead (Pb), copper (Cu), and zinc (Zn)) and pesticides (insecticides, herbicides, and fungicides) adversely influencing the agricultural ecosystem (plant and soil) and human health. Furthermore, heavy metals accumulation and pesticide residues in soils and plants have been discussed in detail. In addition, the characteristics of contaminated soil and plant physiological parameters have been reviewed. Moreover, human diseases caused by exposure to heavy metals and pesticides were also reported. The bioaccumulation, mechanism of action, and transmission pathways of both heavy metals and pesticides are emphasized. In addition, the bioavailability in soil and plant uptake of these contaminants has also been considered. Meanwhile, the synergistic and antagonistic interactions between heavy metals and pesticides and their combined toxic effects have been discussed. Previous relevant studies are included to cover all aspects of this review. The information in this review provides deep insights into the understanding of environmental toxicants and their hazardous effects.

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Section: Effect Of Pesticides Toxicity On Human Healthmentioning

confidence: 99%

Heavy Metals and Pesticides Toxicity in Agricultural Soil and Plants: Ecological Risks and Human Health Implications

Alengebawy

Abdelkhalek

Qureshi

et al. 2021

Toxics

1,020

352

View full text Add to dashboard Cite

show abstract

“…Estudos que avaliaram a exposição a agrotóxicos Poluentes Orgânicos Persistentes (POP) e sua concentração no sangue de indivíduos expostos mostram que existe uma associação para os desfechos de câncer de próstata 31,32 ; câncer de colo do útero 33 , câncer do colo do útero, do útero, da vagina e do ovário 34 .…”

Section: Discussionunclassified

Uso de agrotóxicos e mortalidade por câncer em regiões de monoculturas

et al. 2020

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RESUMO O uso de agrotóxicos na agricultura brasileira é um problema de saúde pública, dadas as contaminações no ambiente, em alimentos e as intoxicações resultantes do uso dessas substâncias. O objetivo deste artigo é investigar a distribuição espacial das áreas plantadas de lavouras e as taxas de mortalidade de alguns tipos de câncer: mama, colo do útero e próstata. Escolheram-se quatro estados brasileiros que possuem grande produção de commodities agrícolas a serem estudadas. Trata-se de um estudo ecológico de análise espacial conduzido com dados e informações do Sistema de Informação sobre Mortalidade (SIM) do Ministério da Saúde, por meio do qual elaboraram-se taxas de mortalidade para os referidos tipos de câncer, cujos óbitos tenham ocorrido entre 1996 e 2016. Há indícios de que existe correspondência entre as áreas de maior estimativa de uso de agrotóxicos Disruptores Endócrinos e o aumento das taxas de mortalidade pelos diferentes tipos de câncer.

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“…77 The high frequency of CVs and CAs observed in the exposed group might result from pesticide-induced oxidative stress. Oxidative stress is known to cause DNA damage, which in turn may cause health disorders including Parkinson's disease, 78 endocrine disruption, 80 respiratory and reproductive disorders, 81 Hodgkin's disease, non-Hodgkin lymphoma, 82 leukemia, Burkitt lymphoma, ovarian cancer, neuroblastoma, soft tissue sarcoma, 83 and cancers of the lung, rectum, stomach, bladder, colon and breast. 84,85 Considering that the mutagenic risk of various cigarette components is considered a confounding factor that can influence the frequency of CVs and CAs, we analyze whether smoking and alcohol consumption in both the exposed and unexposed individuals affect the frequency of chromosomal damage.…”

Section: Cin (%)mentioning

confidence: 99%

<p>Chromosomal Instability in Farmers Exposed to Pesticides: High Prevalence of Clonal and Non-Clonal Chromosomal Alterations</p>

Cepeda

Forero-Castro

Cárdenas-Nieto

et al. 2020

RMHP

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Monitoring of organochlorine pesticides in blood of women with uterine cervix cancer

Cited by 78 publications

References 50 publications

Heavy Metals and Pesticides Toxicity in Agricultural Soil and Plants: Ecological Risks and Human Health Implications

Heavy Metals and Pesticides Toxicity in Agricultural Soil and Plants: Ecological Risks and Human Health Implications

Uso de agrotóxicos e mortalidade por câncer em regiões de monoculturas

<p>Chromosomal Instability in Farmers Exposed to Pesticides: High Prevalence of Clonal and Non-Clonal Chromosomal Alterations</p>

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