Molluscum contagiosum. Eruption following treatment with prednisone and methotrexate

Eyelid molluscum contagiosum presenting as a giant solitary ulcerating mass

“…Giant or atypical lesion molluscum contagiosum may occur in diseases that cause immunosuppression, like the human immunodeficiency virus type 1 (HIV-1) 3 or in patients using immunosuppressive therapy 4 . Such patients are more prone to develop multiple, widespread lesions all over the body such as the face and genital region 5 . Disseminated lesions are more frequently seen in children compared to adults 1…”

Molluscum contagiosum of the eyelid: case report in a man receiving methotrexate and literature review of molluscum contagiosum in patients who are immunosuppressed secondary to methotrexate or HIV infection

“…Individuals receiving immunosuppressive therapies may have an increased risk of developing molluscum contagiosum. Molluscum contagiosum in individuals receiving methotrexate was first identified in 1968 and has since been described in 9 other patients (Table 2) [19][20][21][22][23][24][25][26]. Tumor necrosis factor alpha inhibitors, such as infliximab (Remicade) and etanercept (Enbrel), have also been linked to molluscum contagiosum [27,28].…”

Eruptive molluscum contagiosums in a patient with rheumatoid arthritis and lung cancer

“…The occurrence of multiple MCs during treatment with PSL, MTX, and biologics has been reported [1][2][3][4][5][6], and a few cases of multiple MCs in patients with RA have also been seen [5,6]. A number of studies have shown immunologic dysfunction in RA.…”