Molluscicidal activity of cardiac glycosides from Nerium indicum against Pomacea canaliculata and its implications for the mechanisms of toxicity

Development and Evaluation of Poly Herbal Molluscicidal Extracts for Control of Apple Snail (Pomacea maculata)

“…Glycogen is the primary and intermediate source of energy. The cardiac glycosides of N. indicum decreased acetylcholinesterase (AChE) activities and impaired the hepatopancreas tissues of P. canaliculate, resulting in the fatal inhibition of the activity of digestive enzymes as well as the feeding rate [39,45]. Nicotine acts by mimicking acetylcholine and it exerts a toxic effect in both vertebrates and invertebrates as a neurotoxin by binding to nicotinic acetylcholine receptors and inhibiting their penetration into the synapse [46].…”

“…36 The results indicate that the snails were more sensitive to N. indicum, P. nigrum, and N. tabacum extracts, as evidenced by their lower LC 50 and LC 90 values indicating the highest potency. Eventually, the crude ethanol extract of N. indicum was found to be the most effective, with a LC 90 value (341.57 mg/L, 48 h), whereas Dai et al [39] recorded the lowest LC 50 value (3.71 mg/L, 96 h) with purified cardiac glycosides of N. indicum for the control of P. canaliculata.…”

Relaxing effect of eugenol and essential oils in Pomacea canaliculata

“…Dillapiole, the major constituent of the EO of P. gaudichaudianum, is present in other species of the genus, and its insecticidal activity has previously been described (VOLPE et al, 2016). Natural products, such as glycosides extracted from fresh leaves of Nerium indicum (DAI et al, 2011) and fractions of the methanolic extract of seed flour Camellia oleifera (KIJPRAYOON et al, 2014), also caused P. canaliculata mortality. Molluscicidal effect of the EO Cymbopogon winterianus against Biomphalaria glabrata (RODRIGUES et al, 2013) and the hexane and ethyl acetate extracts from the aerial parts of Atriplex inflata against Galba truncatula (HAMED et al, 2015) have also been described.…”

“…Products extracted from plants are promising alternatives because they are biodegradable and from renewable sources; they also have fewer adverse effects on the ecosystem. There are studies reporting molluscicidal activity of some plant extracts against P. canaliculata (DAI et al, 2011;KIJPRAYOON et al, 2014) and other mollusk species (RODRIGUES et al, 2013;HAMED et al, 2015). In this context, the aim of this study was to evaluate possible molluscicidal and/or relaxing effects of eugenol and the EOs of Origanum majorana, Ocimum americanum, Hesperozygis ringens, and Piper gaudichaudianum on P. canaliculata.…”

Molluscicidal activity of Aglaia duperreana and the constituents of its twigs and leaves

“…The most common method to control this pest in Asian countries is the use of molluscicides and insecticides, which are very toxic to non-target organisms and can destroy the ecosystem [4,5]. Recently, much research attention has been focused on botanic molluscicides because they are biodegradable, easily available, safe for humans, and environmentally friendly [5,6].…”