Molecular mechanisms for the anticancer activity of the carotenoid lycopene

New Developments in Lycopene Analysis by Spectroscopic and Chromatographic Techniques, Accompanied With Mathematical Modelling

“…In these test models, lycopene also suppressed insulin-like growth factor (IGF-I), which is a major autocrine/paracrine mammary and endometrial cancer cell growth regulator [33]. These results agree with those of Sharoni et al [108] related to the influence of lycopene on IGF-I and the risk of prostate and breast cancers.…”

New Developments in Lycopene Analysis by Spectroscopic and Chromatographic Techniques, Accompanied With Mathematical Modelling

“…In these test models, lycopene also suppressed insulin-like growth factor (IGF-I), which is a major autocrine/paracrine mammary and endometrial cancer cell growth regulator [33]. These results agree with those of Sharoni et al [108] related to the influence of lycopene on IGF-I and the risk of prostate and breast cancers.…”

Effect of a Tomato Drink Intervention on Insulin-Like Growth Factor (IGF)-1 Serum Levels in Healthy Subjects

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Lycopene from Tomatoes: Vesicular Nanocarrier Formulations for Dermal Delivery

“…In Figure 5a, intracellular localization of UDV stained with rhodamine can be observed around the nucleus. In fact, Sharoni et al 51 suggested that lycopene or one of its derivatives might interact with members of the nuclear receptor superfamily according to the synergistic inhibition of cancer cell proliferation by lycopene and retinoic acid, two members of this receptor family. Nuclear receptors (RAR and RXR) are ligand-activated transcription factors.…”

New Developments in Lycopene Analysis by Spectroscopic and Chromatographic Techniques, Accompanied With Mathematical Modelling

“…In these test models, lycopene also suppressed insulin-like growth factor (IGF-I), which is a major autocrine/paracrine mammary and endometrial cancer cell growth regulator [33]. These results agree with those of Sharoni et al [108] related to the influence of lycopene on IGF-I and the risk of prostate and breast cancers.…”

Effect of a Tomato Drink Intervention on Insulin-Like Growth Factor (IGF)-1 Serum Levels in Healthy Subjects

“……”

Lycopene from Tomatoes: Vesicular Nanocarrier Formulations for Dermal Delivery

“…In Figure 5a, intracellular localization of UDV stained with rhodamine can be observed around the nucleus. In fact, Sharoni et al 51 suggested that lycopene or one of its derivatives might interact with members of the nuclear receptor superfamily according to the synergistic inhibition of cancer cell proliferation by lycopene and retinoic acid, two members of this receptor family. Nuclear receptors (RAR and RXR) are ligand-activated transcription factors.…”

New Developments in Lycopene Analysis by Spectroscopic and Chromatographic Techniques, Accompanied With Mathematical Modelling

“…In these test models, lycopene also suppressed insulin-like growth factor (IGF-I), which is a major autocrine/paracrine mammary and endometrial cancer cell growth regulator [33]. These results agree with those of Sharoni et al [108] related to the influence of lycopene on IGF-I and the risk of prostate and breast cancers.…”

Effect of a Tomato Drink Intervention on Insulin-Like Growth Factor (IGF)-1 Serum Levels in Healthy Subjects

“……”

Lycopene from Tomatoes: Vesicular Nanocarrier Formulations for Dermal Delivery

“…In Figure 5a, intracellular localization of UDV stained with rhodamine can be observed around the nucleus. In fact, Sharoni et al 51 suggested that lycopene or one of its derivatives might interact with members of the nuclear receptor superfamily according to the synergistic inhibition of cancer cell proliferation by lycopene and retinoic acid, two members of this receptor family. Nuclear receptors (RAR and RXR) are ligand-activated transcription factors.…”