Molecular investigation of macrolide and Tetracycline resistances in oral bacteria isolated from Tunisian children

Kouidhi, Bochra; Zmantar, Tarek; Hentati, Hajer; Najjari, Fayrouz; Mahdouni, Kacem; Bakhrouf, Amina

doi:10.1016/j.archoralbio.2010.09.010

Cited by 14 publications

(14 citation statements)

References 44 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Moreover, transfer of resistance determinants from Enterococci to other more virulent Gram-positive bacteria, like staphylococci, has been observed in vitro [31]. Our previous data supported the presence of resistance oral streptococci [32] and the association of Staphylococcus aureus with dental caries [33] which carried various antibiotics and disinfectants resistance genes [34]. …”

Section: Discussionsupporting

confidence: 72%

Antibiotic resistance and adhesion properties of oral Enterococci associated to dental caries

Kouidhi¹,

Zmantar²,

Mahdouani

et al. 2011

BMC Microbiol

Self Cite

View full text Add to dashboard Cite

BackgroundEnterococci are increasingly associated with opportunistic infections in Humans but the role of the oral cavity as a reservoir for this species is unclear. This study aimed to explore the carriage rate of Enterococci in the oral cavity of Tunisian children and their antimicrobial susceptibility to a broad range of antibiotics together with their adherence ability to abiotic and biotic surfaces.ResultsIn this study, 17 E. faecalis (27.5%) and 4 E. faecium (6.5%) were detected. The identified strains showed resistance to commonly used antibiotics. Among the 17 isolated E. faecalis, 12 strains (71%) were slime producers and 5 strains were non-producers. Among the 4 E. faecium, 2 strains were slime producers. All the tested strains were able to adhere to at least one of the two tested cell lines. Our result showed that 11 E. faecalis and 2 E. faecium strains adhered strongly to Hep-2 as well as to A549 cells.ConclusionsDrugs resistance and strong biofilm production abilities together with a high phenotypic adhesion to host cells are important equipment in E. faecalis and E. faecium which lead to their oral cavity colonization and focal infections.

show abstract

Section: Discussionsupporting

confidence: 72%

Antibiotic resistance and adhesion properties of oral Enterococci associated to dental caries

Kouidhi¹,

Zmantar²,

Mahdouani

et al. 2011

BMC Microbiol

Self Cite

View full text Add to dashboard Cite

show abstract

“…Interestingly, the same study found that certain non-clinical factors initiated antibiotic prescribing for some clinicians, such as unavailability of close appointments and seeking parental satisfaction [ 5 ]. A similar trend was observed in developing countries, where a substantial proportion of dentists prescribe for non-indicated clinical conditions, such as dry socket, localised periapical infection, marginal gingivitis, periodontitis, and pulpitis [ 6 ]. This insufficient knowledge of the appropriate clinical indications is paralleled by lack of awareness of important interventions that promote the optimal use of antibiotics, such as antibiotic stewardship programs [ 5 ].…”

Section: Introductionsupporting

confidence: 56%

Antibiotic Prescribing for Oro-Facial Infections in the Paediatric Outpatient: A Review

et al. 2018

View full text Add to dashboard Cite

There are many reports on the complications associated with antibiotics abuse during the treatment of paediatric patients, particularly those related to antimicrobial resistance. The dental profession is no exception; there is growing evidence that dental practitioners are misusing antibiotics in the treatment of their paediatric patients. This review is directed to dental practitioners who provide oral healthcare to children. It is also directed to medical practitioners, particularly those working in emergency departments and encountering children with acute orofacial infections. A systematic search of literature was conducted to explore the clinical indications and recommended antibiotic regimens for orofacial infections in paediatric outpatients. The main indications included cellulitis, aggressive periodontitis, necrotizing ulcerative gingivitis, and pericoronitis. Amoxicillin was found to be the most commonly recommended antibiotic for short durations of 3–5 days, with metronidazole or azithromycin being the alternative antibiotics in penicillin-sensitive patients.

show abstract

“…Similar trends are also observed in developing countries, where a substantial proportion of dentists prescribe antibiotics for non-indicated clinical conditions [26]. Regionally an indian survey on the use of antibiotics showed that there was over antibiotics endorsing in the absence of following any expert rules, which could be a precedent leading to the global issue of antibiotic resistance [27].…”

Section: Plos Onementioning

confidence: 69%

Antibiotic prescription patterns for treating dental infections in children among general and pediatric dentists in teaching institutions of Karachi, Pakistan

et al. 2020

View full text Add to dashboard Cite

Background Antibiotics are regularly prescribed by dental professionals in their practice, for the purpose of dental treatment as well as for the prevention of infection. The inappropriate use of antibiotics is a significant factor in the rise of antibiotic resistance. There is an immediate need for the advancement of prescribing guidelines and instructive polices to encourage the rational and appropriate utilization of medications especially antibiotics in dentistry. Objective The aim of this study was to identify the frequency of antibiotic prescription for treating dental infections in children among dentists in teaching institutions of Karachi, Pakistan and whether they are adhering to the prescribed international guidelines. Methods A cross-sectional study was conducted in three private and two public colleges of Karachi. After taking written informed consent and checking the inclusion criteria, a total of 380 participants were interviewed using a pre-designed validated questionnaire which included demographic profile and clinical case scenarios. Data were entered and analyzed on SPSS version 20. Inferential analysis was performed using chi-square test. The significance level was set at 0.05. Results Of the 380 subjects, a majority (71.3%) treated 15 or less children per month (n = 271) while 28.7% of dentists (n = 109) treated more than 15 children per month. Overall adherence to American Academy of Pediatric Dentistry guidelines was low from 26.1% to 44.2%. The difference between adherence of dentists with low and high volume of pediatric patients was

show abstract

Molecular investigation of macrolide and Tetracycline resistances in oral bacteria isolated from Tunisian children

Cited by 14 publications

References 44 publications

Antibiotic resistance and adhesion properties of oral Enterococci associated to dental caries

Antibiotic resistance and adhesion properties of oral Enterococci associated to dental caries

Antibiotic Prescribing for Oro-Facial Infections in the Paediatric Outpatient: A Review

Antibiotic prescription patterns for treating dental infections in children among general and pediatric dentists in teaching institutions of Karachi, Pakistan

Contact Info

Product

Resources

About