Molecular detection and genetic characterization of ovine gammaherpesvirus-2 (OvHV-2) in sheep in the Philippines

Mananguit, Innina R.; Bartolome, Nest Dale F.; Tubalinal, Gabriel Alexis S.P.; Mingala, Claro N.

doi:10.1016/j.smallrumres.2021.106383

Cited by 1 publication

(2 citation statements)

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“…Based on the results of BLAST and phylogenetic analysis, the sequences obtained in this study showed approximately 98-100% similarity to other published sequences of the ORF75 tegument protein gene internationally. These ndings support other researchers' ndings that there is no major difference between OvHV-2 sequences globally [14,19,31].…”

Section: Discussionsupporting

confidence: 91%

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Molecular epidemiolgy of ovine herpesvirus-2 in small ruminants, Sistan region, Iran

Abdollahi,

Saadati,

Rasekh

et al. 2024

Preprint

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Malignant catarrhal fever (MCF) is a systemic, sporadic, and fatal viral disease affecting susceptible hosts such as cattle, buffalo, deer, etc. Ovine herpesvirus-2 (OvHV-2) is the main cause of MCF in livestock. OvHV-2 infects sheep and goats asymptomatically, playing a significant role in the virus circulation. in this study the prevalence of OvHV-2 in sheep (n:42) and goats(n:52) through molecular tests conducted in the Sistan region located in the north of Sistan&- Baluchestan province, Iran. OvHV-2 POL and ORF75 Tegument Protein genes were detected in 15/100 samples through Hemi-Nested PCR (15%). BLAST results show 100% identity to the isolations reports from Pakistan (MK852172), Brazil (OP121121), Turkey (MN419921), Egypt (ON952534) and India (OR762746). There was no significant relationship between the virus prevalence and independent variables, including species, age and gender of the animal, clinical symptoms, herd size and location of livestock. These findings indicate that OvHV-2 is circulating in the Sistan region, causing MCF. Since traditional livestock farming is common in the region, carrier species and susceptible hosts are kept together, which is a risk factor for virus transmission to susceptible hosts like cattle. To control and prevent the disease, it is essential to consider separating different livestock species in the region.

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Section: Discussionsupporting

confidence: 91%

“…Additionally, Li et al ( 2001) indicated that OvHV-2 can infect fetuses during pregnancy [27], as reported by Pekmez et al [24]. The ndings for the virus in different age groups suggest that the virus is endemic to the area, as reported by Mananguit et al in Philippines [31] and Khudhair in Iraq [14].…”

Section: Discussionmentioning

confidence: 82%