Molecular aspects of skin aging. Literature review

Rogowski-Tylman, Michał; Woźniacka, Anna; Lesiak, Aleksandra

doi:10.5114/dr.2016.59136

Cited by 2 publications

(3 citation statements)

References 26 publications

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“…86 Different enzymes are reported to degrade collagen in the extracellular matrix of skin. 87 Brandt et al 88 demonstrated the difficulties of microscopic species determination of archaeological skin objects preserved in bogs. They proposed mass spectrometrybased peptide sequencing as a valid method.…”

Section: Collagen-containing Materialsmentioning

confidence: 99%

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Recent developments in using the molecular decay dating method: a review

Tintner

2021

Annals of the New York Academy of Sciences

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The dating of organic findings is a fundamental task for many scientific fields. Radiocarbon dating is currently the most commonly used method. For wood, dendrochronology is another state-of-the-art method. Both methods suffer from systematic restrictions, leading to samples that have not yet been able to be dated. Molecular changes over time are reported for many materials under different preservation conditions. Many of them are intrinsically monotonous. These monotonous molecular decay (MD) patterns can be understood as clocks that start at the time when a given molecule was formed. Factors that influence these clocks include input material composition and preservation conditions. Different wood species, degrees of pyrolysis, and pretreatments lead to different prediction models. Preservation conditions might change the speed of a given clock and lead to different prediction models. Currently published models for predicting the age of wood, paper, and parchment depend on infrared spectroscopy. In contrast to radiocarbon dating, dating via MD does not comprise a single methodology. Some clocks may deliver less precise results than the others. Ultimately, developing a completely different, new dating strategy-such as MD dating-will help to bring to light a treasure trove of information hidden in the darkness of organic findings.

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Section: Collagen-containing Materialsmentioning

confidence: 99%

“…In addition to internal aging effects, the exposure to air and especially UV light fosters these processes, making the skin less elastic, wrinkled, stiffened, and less able to recoil 86 . Different enzymes are reported to degrade collagen in the extracellular matrix of skin 87 . Brandt et al 88 .…”

Section: Datingmentioning

confidence: 99%

Recent developments in using the molecular decay dating method: a review

Tintner

2021

Annals of the New York Academy of Sciences

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“…Antioxidant strategies are often used to prevent skin cancer and premature skin aging by inhibiting/spreading photo-oxidative reactions. Supplementation with compounds of plant origin and with pure molecules with recognized antioxidant potential is quite frequent [29]. Plant extracts effectively protect against the effects of sun exposure [30] [31] [32].…”

Section: Introductionmentioning

confidence: 99%

Performance of Cosmetic Ingredients Evaluated by Their Membrane Protection Efficiency

Silva¹,

Cabello²,

Severino³

et al. 2021

JCDSA

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Plant extracts (PEs) are frequently used as ingredients in skin and hair care products to improve protection against the excess of sun exposure. PEs are usually selected based on their antioxidant capacity for reducing the damage in lipids and proteins, which are key molecules in the maintenance of skin homeostasis and hair integrity. Interestingly, biomolecules that do not have any antioxidant capacity can have a protective effect by physically adsorbing and inhibiting leakage of membranes. Our aims are: 1) to develop an experimental protocol that quantifies the level of membrane damage/protection; 2) to recommend an approach to compare the membrane protection efficiency of different PEs; 3) to briefly describe the mechanisms of membrane protection. Evaluation of membrane damage/protection is based on a phospholipid liposome system that signals the membrane rupture caused by photo-induced lipid oxidation. Carboxyfluorescein (CF) emission is monitored as a function of time (120 min) in a controlled experimental setup, in which a certain level of membrane damage is induced by Dimethyl-Methylene Blue (DMMB) photosensitized oxidation during red-light irradiation. Percentage levels of membrane damage/protection are calculated by comparing the CF fluorescence level of DMMB-liposomes in the presence of varying concentrations of membrane-protective ingredients with that of surfactant-dissolved DMMB-liposomes. Membrane protectants reduce the level of CF fluorescence during irradiation of DMMB-liposomes. Gallic acid (GA) and trehalose (Tre) were used as standard compounds to compute the levels of protection by the antioxidant and physical adsorption mechanisms, respectively. The percentage of membrane protection was shown to be linearly proportional to the concentration of the standard protectants. The performance of PEs was measured and compared in terms of GA or Tre membrane protection equivalents. All extracted also had their antioxidant capacities evaluate by the anti-radical DPPH assay. The mem-*Contributed equally to the manuscript.

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Molecular aspects of skin aging. Literature review

Cited by 2 publications

References 26 publications

Recent developments in using the molecular decay dating method: a review

Recent developments in using the molecular decay dating method: a review

Performance of Cosmetic Ingredients Evaluated by Their Membrane Protection Efficiency

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