Modulation of control of muscle sympathetic nerve activity during orthostatic stress in humans

Ichinose, Masashi; Saito, Mitsuru; Ogawa, Takeshi; Hayashi, Keiji; Kondo, Narihiko; Nishiyasu, Takeshi

doi:10.1152/ajpheart.00215.2004

Cited by 23 publications

(39 citation statements)

References 38 publications

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“…Therefore, it seems obvious that similar response from MI sequence could not occur and parallel those observed during actual trunk movement eliciting orthostatic hypotension. Ichinose et al (2004) and Kamiya et al (2005) suggested that the upward resetting of arterial baroreflex control in response to orthostatic stress facilitates the activation of sympathetic nerve activity, thereby contributing to the prevention of postural hypotension. Muscle sympathetic nerve activity progressively increases in response to increasing orthostatic stress through the gradual upward resetting of arterial baroreflex control.…”

Section: The Autonomic Nervous System: a Witness Of Movement Observatmentioning

confidence: 99%

Autonomic nervous system correlates in movement observation and motor imagery

Collet

Rienzo

Hoyek

et al. 2013

Front. Hum. Neurosci.

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The purpose of the current article is to provide a comprehensive overview of the literature offering a better understanding of the autonomic nervous system (ANS) correlates in motor imagery (MI) and movement observation. These are two high brain functions involving sensori-motor coupling, mediated by memory systems. How observing or mentally rehearsing a movement affect ANS activity has not been extensively investigated. The links between cognitive functions and ANS responses are not so obvious. We will first describe the organization of the ANS whose main purposes are controlling vital functions by maintaining the homeostasis of the organism and providing adaptive responses when changes occur either in the external or internal milieu. We will then review how scientific knowledge evolved, thus integrating recent findings related to ANS functioning, and show how these are linked to mental functions. In turn, we will describe how movement observation or MI may elicit physiological responses at the peripheral level of the autonomic effectors, thus eliciting autonomic correlates to cognitive activity. Key features of this paper are to draw a step-by step progression from the understanding of ANS physiology to its relationships with high mental processes such as movement observation or MI. We will further provide evidence that mental processes are co-programmed both at the somatic and autonomic levels of the central nervous system (CNS). We will thus detail how peripheral physiological responses may be analyzed to provide objective evidence that MI is actually performed. The main perspective is thus to consider that, during movement observation and MI, ANS activity is an objective witness of mental processes.

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Section: The Autonomic Nervous System: a Witness Of Movement Observatmentioning

confidence: 99%

Autonomic nervous system correlates in movement observation and motor imagery

Collet

Rienzo

Hoyek

et al. 2013

Front. Hum. Neurosci.

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“…During mild to moderate central hypovolemia, the operating point of baroreflex-mediated control of sympathetic nerve activity is shifted upward without a change in gain, such that sympathetic nerve activity is increased at any given DAP (Ichinose et al, 2004a,b). Additionally, there is a tighter coupling between oscillations in arterial blood pressure and MSNA, as quantitated using cross-spectral analysis by an increase in the coherence function between these variables (Furlan et al, 2000; Kamiya et al, 2005; Cooke et al, 2009).…”

Section: Msna At Hemodynamic Decompensationmentioning

confidence: 99%

Sympathetic Responses to Central Hypovolemia: New Insights from Microneurographic Recordings

Ryan¹,

Rickards²,

Hinojosa‐Laborde³

et al. 2012

Front. Physio.

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Hemorrhage remains a major cause of mortality following traumatic injury in both military and civilian settings. Lower body negative pressure (LBNP) has been used as an experimental model to study the compensatory phase of hemorrhage in conscious humans, as it elicits central hypovolemia like that induced by hemorrhage. One physiological compensatory mechanism that changes during the course of central hypovolemia induced by both LBNP and hemorrhage is a baroreflex-mediated increase in muscle sympathetic nerve activity (MSNA), as assessed with microneurography. The purpose of this review is to describe recent results obtained using microneurography in our laboratory as well as those of others that have revealed new insights into mechanisms underlying compensatory increases in MSNA during progressive reductions in central blood volume and how MSNA is altered at the point of hemodynamic decompensation. We will also review recent work that has compared direct MSNA recordings with non-invasive surrogates of MSNA to determine the appropriateness of using such surrogates in assessing the clinical status of hemorrhaging patients.

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“…Large increases of baroreflex gain occur when supine subjects sleep (Smyth et al , 1969, Pagani et al , 1988), and when upright subjects abruptly return to the supine position (Westerhof et al , 2006). Moreover, simple repeated estimates of vagal baroreflex gain in subjects who are, as well as can be determined, in a ‘steady-state’, document surprisingly large ongoing fluctuations of vagal baroreflex gain (Yamamoto et al , 1989, Badra et al , 2001, Ichinose et al , 2004, Eckberg & Kuusela 2005). …”

Section: Discussionmentioning

confidence: 99%

Human baroreflex rhythms persist during handgrip and muscle ischaemia

et al. 2013

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Aim To determine if physiological, rhythmic fluctuations of vagal baroreflex gain persist during exercise, post-exercise ischaemia, and recovery. Methods We studied responses of six supine healthy men and one woman to a stereotyped protocol comprising rest, handgrip exercise at 40 % maximum capacity to exhaustion, post-exercise forearm ischaemia, and recovery. We measured electrocardiographic R-R intervals, photoplethysmographic finger arterial pressures, and peroneal nerve muscle sympathetic activity. We derived vagal baroreflex gains from a sliding (25 s window moved by 2 s steps) systolic pressure – R-R interval transfer function at 0.04 – 0.15 Hz. Results Vagal baroreflex gain oscillated at low, nearly constant frequencies throughout the protocol (at ~ 0.06 Hz – a period of about 18 s); however, during exercise, most oscillations were at low gain levels, and during ischaemia and recovery, most oscillations were at high gain levels. Conclusions Vagal baroreflex rhythms are not abolished by exercise, and they are not overwhelmed after exercise during ischaemia and recovery.

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Modulation of control of muscle sympathetic nerve activity during orthostatic stress in humans

Cited by 23 publications

References 38 publications

Autonomic nervous system correlates in movement observation and motor imagery

Autonomic nervous system correlates in movement observation and motor imagery

Sympathetic Responses to Central Hypovolemia: New Insights from Microneurographic Recordings

Human baroreflex rhythms persist during handgrip and muscle ischaemia

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