Modes of administration of antibiotics for symptomatic severe urinary tract infections

Abstract

Cochrane Database of Systematic Reviews Modes of administration of antibiotics for symptomatic severe urinary tract infections (Review) Pohl A Pohl A. Modes of administration of antibiotics for symptomatic severe urinary tract infections.

Optimizing Antibiotic Use for Urinary Tract Infections: A Qualitative Assessment of Regular Prescribing Practices

“…UTIs can be effectively treated using oral antibiotics, even in severe cases, as studies have shown no difference in outcomes compared to that of injectable therapy. 31 Moreover, oral antibiotic use can help minimize hospital stays, lower healthcare costs, and reduce the risk of complications associated with IV therapy. 26 32 33 To decrease the prescription rate of IV antibiotics for lower UTIs, we emphasized the effectiveness and safety of oral antibiotics in messages sent to emergency departments.…”

Optimizing Antibiotic Use for Urinary Tract Infections: A Qualitative Assessment of Regular Prescribing Practices

“…UTIs can be effectively treated using oral antibiotics, even in severe cases, as studies have shown no difference in outcomes compared to that of injectable therapy. 31 Moreover, oral antibiotic use can help minimize hospital stays, lower healthcare costs, and reduce the risk of complications associated with IV therapy. 26 32 33 To decrease the prescription rate of IV antibiotics for lower UTIs, we emphasized the effectiveness and safety of oral antibiotics in messages sent to emergency departments.…”

Complicated urinary tract infections

“…A recently published Cochrane review analyzed all randomized controlled trials to assess whether the mode of administration of antibiotic therapy for severe UTI has an effect on cure rate, reinfection rate, and kidney scarring [23]. For unclear reasons, the review excluded studies involving only patients with complicated UTI, with the assumption that the underlying bacterial spectrum differed from that of uncomplicated UTI.…”

Intravenous antibiotics for urinary tract infections in children with neurologic impairment

“…They were also more likely to require ICU admission, have a higher severity of illness, and have a longer LOS, with a median of 5 (IQR [4,7]) days compared to 2 (IQR [2,3]) days for patients who received short IV courses. The median (inter-quartile range) exposure length of IV antibiotics was 2 (2, 3) days in the shortcourse group and 5 (4, 7) days in the long-course group.…”

Optimizing Antibiotic Use for Urinary Tract Infections: A Qualitative Assessment of Regular Prescribing Practices

“…UTIs can be effectively treated using oral antibiotics, even in severe cases, as studies have shown no difference in outcomes compared to that of injectable therapy. 31 Moreover, oral antibiotic use can help minimize hospital stays, lower healthcare costs, and reduce the risk of complications associated with IV therapy. 26 32 33 To decrease the prescription rate of IV antibiotics for lower UTIs, we emphasized the effectiveness and safety of oral antibiotics in messages sent to emergency departments.…”

Complicated urinary tract infections

“…A recently published Cochrane review analyzed all randomized controlled trials to assess whether the mode of administration of antibiotic therapy for severe UTI has an effect on cure rate, reinfection rate, and kidney scarring [23]. For unclear reasons, the review excluded studies involving only patients with complicated UTI, with the assumption that the underlying bacterial spectrum differed from that of uncomplicated UTI.…”

Intravenous antibiotics for urinary tract infections in children with neurologic impairment

“…They were also more likely to require ICU admission, have a higher severity of illness, and have a longer LOS, with a median of 5 (IQR [4,7]) days compared to 2 (IQR [2,3]) days for patients who received short IV courses. The median (inter-quartile range) exposure length of IV antibiotics was 2 (2, 3) days in the shortcourse group and 5 (4, 7) days in the long-course group.…”

Optimizing Antibiotic Use for Urinary Tract Infections: A Qualitative Assessment of Regular Prescribing Practices

“…UTIs can be effectively treated using oral antibiotics, even in severe cases, as studies have shown no difference in outcomes compared to that of injectable therapy. 31 Moreover, oral antibiotic use can help minimize hospital stays, lower healthcare costs, and reduce the risk of complications associated with IV therapy. 26 32 33 To decrease the prescription rate of IV antibiotics for lower UTIs, we emphasized the effectiveness and safety of oral antibiotics in messages sent to emergency departments.…”

Complicated urinary tract infections

“…A recently published Cochrane review analyzed all randomized controlled trials to assess whether the mode of administration of antibiotic therapy for severe UTI has an effect on cure rate, reinfection rate, and kidney scarring [23]. For unclear reasons, the review excluded studies involving only patients with complicated UTI, with the assumption that the underlying bacterial spectrum differed from that of uncomplicated UTI.…”

Intravenous antibiotics for urinary tract infections in children with neurologic impairment

“…They were also more likely to require ICU admission, have a higher severity of illness, and have a longer LOS, with a median of 5 (IQR [4,7]) days compared to 2 (IQR [2,3]) days for patients who received short IV courses. The median (inter-quartile range) exposure length of IV antibiotics was 2 (2, 3) days in the shortcourse group and 5 (4, 7) days in the long-course group.…”