Modern treatment of severe "shrinkage of the conjunctiva".

Sir Benjamin William Rycroft OBE (1902–1967): British ophthalmologist and pioneer in corneal surgery

“…Rycroft went on to explain how the treatment would then vary depending on the form. 32 Despite only recently entering the world of ophthalmology, it did not take long for the industrious Benjamin to start making a name for himself. His devotion to the specialty along with his honesty, efficiency and kindness made him popular and well-known amongst his colleagues.…”

“…Pemphigus is a rare condition where the immune system attacks a patient's epidermis causing painful blisters all over the body. 32 Benjamin wrote various journal papers over his career on the management of ocular blisters where he analytically discussed the different treatment options. His landmark 1934 paper on pemphigus helped establish his reputation as he was the first person to divide conjunctival pemphigus into two forms [acute and chronic].…”

Sir Benjamin William Rycroft OBE (1902–1967): British ophthalmologist and pioneer in corneal surgery

“…Rycroft went on to explain how the treatment would then vary depending on the form. 32 Despite only recently entering the world of ophthalmology, it did not take long for the industrious Benjamin to start making a name for himself. His devotion to the specialty along with his honesty, efficiency and kindness made him popular and well-known amongst his colleagues.…”

“…Pemphigus is a rare condition where the immune system attacks a patient's epidermis causing painful blisters all over the body. 32 Benjamin wrote various journal papers over his career on the management of ocular blisters where he analytically discussed the different treatment options. His landmark 1934 paper on pemphigus helped establish his reputation as he was the first person to divide conjunctival pemphigus into two forms [acute and chronic].…”

BENIGN MUCOUS MEMBRANE PEMPHIGOID II. Cytology

“…This diffuse, unspecific inflammation, mainly of a chronic character, is much more pronounced than in pemphigus (Werf 1966). In the submucosal conjunctival stroma, pronounced fibrosis is also noticed, which entails cicatricial shrinkage (Andersen 1959, Taylor 1967. At the same time, changes occur in the epithelium, which either becomes atrophic, with only few cell layers (McCarthy 1972), or irregularly thickened.…”

“…Associated epidermoid changes are frequently present, manifesting themselves by a pronounced stratum granulosum and in some instances, keratinisation. Further, the basal membrane will often be destroyed and have disappeared (Taylor 1967). These changes are diffuse, but Jamieson (1961) has often detected circumscribed leucoplakia as well in BMMP.…”

“…Such changes are epithelial detachment from Bowman's membrane, in some cases formation of bullae and ulceration; and further, invasion of vascularized granulation tissue with the same cellular infiltration. Subsequently, the thickened epithelium grows horny, while Bowman's membrane becomes destroyed and the subjacent stroma becomes fibrous (Duke-Elder 1965, Taylor 1967.…”

Sir Benjamin William Rycroft OBE (1902–1967): British ophthalmologist and pioneer in corneal surgery

“…Rycroft went on to explain how the treatment would then vary depending on the form. 32 Despite only recently entering the world of ophthalmology, it did not take long for the industrious Benjamin to start making a name for himself. His devotion to the specialty along with his honesty, efficiency and kindness made him popular and well-known amongst his colleagues.…”

“…Pemphigus is a rare condition where the immune system attacks a patient's epidermis causing painful blisters all over the body. 32 Benjamin wrote various journal papers over his career on the management of ocular blisters where he analytically discussed the different treatment options. His landmark 1934 paper on pemphigus helped establish his reputation as he was the first person to divide conjunctival pemphigus into two forms [acute and chronic].…”

BENIGN MUCOUS MEMBRANE PEMPHIGOID II. Cytology

“…This diffuse, unspecific inflammation, mainly of a chronic character, is much more pronounced than in pemphigus (Werf 1966). In the submucosal conjunctival stroma, pronounced fibrosis is also noticed, which entails cicatricial shrinkage (Andersen 1959, Taylor 1967. At the same time, changes occur in the epithelium, which either becomes atrophic, with only few cell layers (McCarthy 1972), or irregularly thickened.…”

“…Associated epidermoid changes are frequently present, manifesting themselves by a pronounced stratum granulosum and in some instances, keratinisation. Further, the basal membrane will often be destroyed and have disappeared (Taylor 1967). These changes are diffuse, but Jamieson (1961) has often detected circumscribed leucoplakia as well in BMMP.…”

“…Such changes are epithelial detachment from Bowman's membrane, in some cases formation of bullae and ulceration; and further, invasion of vascularized granulation tissue with the same cellular infiltration. Subsequently, the thickened epithelium grows horny, while Bowman's membrane becomes destroyed and the subjacent stroma becomes fibrous (Duke-Elder 1965, Taylor 1967.…”

Sir Benjamin William Rycroft OBE (1902–1967): British ophthalmologist and pioneer in corneal surgery

“…Rycroft went on to explain how the treatment would then vary depending on the form. 32 Despite only recently entering the world of ophthalmology, it did not take long for the industrious Benjamin to start making a name for himself. His devotion to the specialty along with his honesty, efficiency and kindness made him popular and well-known amongst his colleagues.…”

“…Pemphigus is a rare condition where the immune system attacks a patient's epidermis causing painful blisters all over the body. 32 Benjamin wrote various journal papers over his career on the management of ocular blisters where he analytically discussed the different treatment options. His landmark 1934 paper on pemphigus helped establish his reputation as he was the first person to divide conjunctival pemphigus into two forms [acute and chronic].…”

BENIGN MUCOUS MEMBRANE PEMPHIGOID II. Cytology

“…This diffuse, unspecific inflammation, mainly of a chronic character, is much more pronounced than in pemphigus (Werf 1966). In the submucosal conjunctival stroma, pronounced fibrosis is also noticed, which entails cicatricial shrinkage (Andersen 1959, Taylor 1967. At the same time, changes occur in the epithelium, which either becomes atrophic, with only few cell layers (McCarthy 1972), or irregularly thickened.…”

“…Associated epidermoid changes are frequently present, manifesting themselves by a pronounced stratum granulosum and in some instances, keratinisation. Further, the basal membrane will often be destroyed and have disappeared (Taylor 1967). These changes are diffuse, but Jamieson (1961) has often detected circumscribed leucoplakia as well in BMMP.…”

“…Such changes are epithelial detachment from Bowman's membrane, in some cases formation of bullae and ulceration; and further, invasion of vascularized granulation tissue with the same cellular infiltration. Subsequently, the thickened epithelium grows horny, while Bowman's membrane becomes destroyed and the subjacent stroma becomes fibrous (Duke-Elder 1965, Taylor 1967.…”