2009
DOI: 10.1016/j.ejpain.2008.12.003
|View full text |Cite
|
Sign up to set email alerts
|

Abstract: Back pain with neuropathic components is likely to affect a relevant proportion of the general adult population and cause a disproportionately high share of back pain-related costs.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1

Citation Types

1
59
0
5

Year Published

2010
2010
2021
2021

Publication Types

Select...
6
2
1

Relationship

0
9

Authors

Journals

citations
Cited by 86 publications
(65 citation statements)
references
References 31 publications
1
59
0
5
Order By: Relevance
“…Within the pain system, we do not fully appreciate the pro-and anti-nociceptive properties and do not yet fully know how to interact pharmaceutically within the 'pain cascade'. Long-term pain in particular is often a heterogeneous condition involving many different processes and a neuropathic pain component is often involved, for example in chronic back pain, resulting in more severe, complex, and costly treatment 28 . Moreover, psychological factors can exacerbate chronic pain.…”
Section: The Pain Systemmentioning
confidence: 99%
“…Within the pain system, we do not fully appreciate the pro-and anti-nociceptive properties and do not yet fully know how to interact pharmaceutically within the 'pain cascade'. Long-term pain in particular is often a heterogeneous condition involving many different processes and a neuropathic pain component is often involved, for example in chronic back pain, resulting in more severe, complex, and costly treatment 28 . Moreover, psychological factors can exacerbate chronic pain.…”
Section: The Pain Systemmentioning
confidence: 99%
“…This distinction has important clinical implications because of the different mechanisms involved. Neuropathic pain (e.g., post-herpetic neuralgia, trigeminal neuralgia) is associated with more intense and prolonged pain, more severe co-morbidity and poorer quality of life 34,35 , as a result of trophic and structural changes and central sensitisation 36 . These patients experience persistent, spontaneous, lancinating pain caused by ectopic discharge, primarily in A fibres, while central sensitisation may cause hyperalgesia and allodynia 33 .…”
Section: Mechanism-orientated Pain Treatmentmentioning
confidence: 99%
“…Thus, recent studies have demonstrated that approximately 20-55% of patients with chronic LBP have a 490% likelihood of a neuropathic pain component 14,[17][18][19][20] , and, in an additional 28% of patients, a neuropathic pain component is suspected 17 . The presence of a neuropathic pain component is associated with more severe pain symptoms 14 and higher healthcare utilization costs 21 . Multiple treatment approaches for chronic LBP exist, both non-pharmacological (e.g.…”
Section: I a L D I S T R I B U T I O N U N A U T H O R I Z E D U S mentioning
confidence: 99%