2010
DOI: 10.1007/978-3-642-11712-1_7
View full text
|
|
Share

Abstract: Abstract. In this work we present a Bio-PEPA model describing the Nuclear Factor κB (NF-κB) signalling pathway. In particular our model focuses on the dynamic response of NF-κB to an external stimulus. Each biochemical species in the pathway is represented by a specific Bio-PEPA component and the external stimulus is abstracted by time-dependent Bio-PEPA events describing the start and the end of the signal. The Bio-PEPA model is a formal intermediate representation of the pathway on which various kinds of an…

Expand abstract