Modeling the dynamic kinetics of microbial disinfection with dissipating chemical agents—a theoretical investigation

Peleg, Micha

doi:10.1007/s00253-020-11042-8

Cited by 24 publications

(16 citation statements)

References 32 publications

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“…in which t 1 is the time of rate change from k 1 to k 2 [33]. Note that similar or almost identical parameter values (k 1 and k 2 ) should be obtained when Eqs.…”

Section: Observation Of Non-linear Survival Curves and Some Non-linear Modelsmentioning

confidence: 68%

The Weibull Model for Microbial Inactivation

Buzrul

2021

Food Eng Rev

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The first-order kinetics for microbial inactivation was derived more than 100 years ago and is still used, although more and more researchers are aware of very common non-linear survival curves. The Weibull model is just a simple alternative to the linear model and can be used to describe convex, concave, and linear survival curves. The objective of this review is not to criticize the first-order kinetics or to praise the Weibull model. In this review, the Peleg and Mafart versions of the Weibull model were compared with emphasis on the parameters of those model expressions, the scaled sensitivity coefficients of the model parameters, and the dependency of the model parameters to each other. Secondary modeling was also considered. It was concluded that both Peleg and Mafart versions can be safely used to describe linear and non-linear (convex or concave) survival curves under constant conditions. However, concerning the secondary model, predictions under dynamic conditions, and availability of an Excel®-based workbook for this purpose, the Peleg model seemed to be one step ahead. One of the parameters of the Weibull model and the secondary model derived from this parameter could be used as an alternative to the conventional D value. This work confirms that the Weibull model can serve as the microbial survival model instead of the now obsolete linear model whatever the lethal treatment is.

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“…in which t 1 is the time of rate change from k 1 to k 2 [33]. Note that similar or almost identical parameter values (k 1 and k 2 ) should be obtained when Eqs.…”

Section: Observation Of Non-linear Survival Curves and Some Non-linear Modelsmentioning

confidence: 68%

The Weibull Model for Microbial Inactivation

Buzrul

2021

Food Eng Rev

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“…Oldenburg et al compared the fitting effects of the Chick-Watson model, Home model and series-event model on the AOB characteristic curves of monochloramine inactivation, and finally found that the Chick-Watson model was the most consistent with the actual data. On this basis, the n-order Chick-Watson model [15] is used to fit the characteristic curve of monochloramine-inactivated N. europaea at different pH. All results proved that the first-order Chick-Watson model to be enough to obtain a good fitting effect [11].…”

Section: Introductionmentioning

confidence: 82%

“…The Chick-Watson model has been proven to be effective in many studies; its mathematical properties and application to disinfectants, such as chlorine, ozone, hydrogen peroxide, copper and ethanol, have been described and discussed [21][22][23][24][25]. However, it requires separately determining the disinfection rate constant for each pH and temperature combination [14,15,26], which may reduce the versatility of the model. Therefore, this equation model was modified when inactivation rate constant k was integrated as a function of pH and temperature, yielding the following functional relationship:…”

Section: Development Of the Disinfection Kinetic Modelmentioning

confidence: 99%

Disinfection Kinetics of Free Chlorine, Monochloramines and Chlorine Dioxide on Ammonia-Oxidizing Bacterium Inactivation in Drinking Water

Zhang¹,

Qiu²,

Xu³

et al. 2021

Water

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With the widespread use of chloramines disinfection, nitrification has become a problem that cannot be ignored. In order to control nitrification in the drinking water distribution system (DWDS), the inactivation effect of free chlorine, monochloramine and chlorine dioxide on ammonia-oxidizing bacterium (AOB) was studied under different temperature (8 °C, 26 °C and 35 °C) and pH (6.0, 7.0 and 8.7) conditions. The inactivation effect of Nitrosomonas europaea (a kind of AOB) by the three disinfectants increases with increasing temperature. As for the raised pH, the inactivation effect of free chlorine and monochloramine on AOB decreased, while that of chlorine dioxide increased. Last, but certainly not least, the experimental data of the disinfection were calculated to develop the N. europaea inactivation kinetic model, which was based on the first order Chick–Watson equation. The proposed model in this study took the two variables, pH and temperature, into consideration simultaneously, which were used to evaluate the average Ct value (multiplying the concentration of the residual disinfectant by the time of contact with N. europaea) required for different disinfectants when they produced the ideal inactivation effect on N. europaea.

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“…In systems with simpler vitamin D3 degradation (all tested conditions except light and oxygen), it was comparable to the first-order model, which was used primarily for its simplicity. The Weibull model has lately found useful application in fields such as modelling microbial reactions [ 49 , 50 , 51 ], survival analysis [ 52 , 53 , 54 ], and engineering and materials [ 55 , 56 , 57 , 58 ], but it has rarely been applied to stability data [ 59 ].…”

Section: Discussionmentioning

confidence: 99%

Comprehensive Stability Study of Vitamin D3 in Aqueous Solutions and Liquid Commercial Products

et al. 2021

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Vitamin D3 has numerous beneficial effects, such as musculoskeletal, immunomodulatory, and neuroprotective. However, its instability is the main obstacle to formulating quality products. Despite increased attention and growing use, data on vitamin D3 stability is scarce because data from individual studies is inconclusive and mostly qualitative. Therefore, we have systematically investigated the influence of various factors (temperature, light, oxygen, pH, concentration, and metal ions) on its stability in aqueous media using a stability-indicating HPLC-UV method. First-order kinetics fitted its degradation under all tested conditions except light and oxygen. In both cases, the established models in chemical kinetics were inappropriate and upgraded with the Weibull model. Metal ions and acidic conditions had the main destabilizing effect on vitamin D3 in aqueous media, but these solutions were successfully stabilized after the addition of ethylenediaminetetraacetic acid (EDTA), ascorbic acid, and citric acid, individually and in combination. EDTA showed the most significant stabilizing effect. Synergism among antioxidants was not observed. Our findings on vitamin D3 instability in aqueous media also correlated with its instability in commercial products. Vitamin D3 aqueous products require proper stabilization, thereby signifying the importance and contribution of the obtained results to the formulation of stable and quality products.

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Modeling the dynamic kinetics of microbial disinfection with dissipating chemical agents—a theoretical investigation

Cited by 24 publications

References 32 publications

The Weibull Model for Microbial Inactivation

The Weibull Model for Microbial Inactivation

Disinfection Kinetics of Free Chlorine, Monochloramines and Chlorine Dioxide on Ammonia-Oxidizing Bacterium Inactivation in Drinking Water

Comprehensive Stability Study of Vitamin D3 in Aqueous Solutions and Liquid Commercial Products

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