Modeling aerosol transmission of SARS-CoV-2 in multi-room facility

Kennedy, Matthew; Lee, Sung‐Jin; Epstein, Michael

doi:10.1016/j.jlp.2020.104336

Cited by 27 publications

(44 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Nine of the filtration studies were modelling, employing the following models: one-dimensional analytical model, 41 Wells-Riley model, [42][43][44][45] CONTAM multi-zone IAQ model, 46 Susceptible-Exposed-Infectious-Recovered (SEIR) model, 43 an indoor contact model, 43 a control volume conservation model, 47 Hybrid Single Particle Lagrangian Integrated Trajectory (HYSPLIT) model, 48 School Building Archetype (SBA) model using both the Wells-Riley and Monte-Carlo approaches, 44 the multi-region FATE model of Fauske & Associates, 45 and doseresponse model. 49 Viruses investigated include SARS-CoV-2, 45,49 measles with influenza size distributions, 44 influenza, [42][43]46 rhinovirus, 46 PRRSV, 47 avian influenza, 48 and virus modelled as gas. 41 Augenbraun et al 49 sought to examine SARS-CoV-2 but the relevant infectivity parameters were set to that of influenza.…”

Section: Resultsmentioning

confidence: 99%

“…One study found that the use of filtration was associated with decreased attack rate. 43 Two studies found HEPA filtration was associated with decreased risk of SARS-CoV-2 infection 45 and decreased probability of SARS-CoV-2 infection. 49 Finally, Janni et al 47 found that a combination of MERV 8 prefilter and MERV 16 was associated with a lower concentration of PRRSV compared to a combination of MERV 8 prefilter and MERV 14.…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

The impact of heating, ventilation, and air conditioning design features on the transmission of viruses, including the 2019 novel coronavirus: a systematic review of filtration

Thornton

Fleck

Kroeker

et al. 2021

Preprint

View full text Add to dashboard Cite

Historically, viruses have demonstrated airborne transmission. Emerging evidence suggests the novel coronavirus (SARS-CoV-2) that causes COVID-19 may also spread by airborne transmission. This is more likely in indoor environments, particularly with poor ventilation. In the context of potential airborne transmission, a vital mitigation strategy for the built environment is heating, ventilation, and air conditioning (HVAC) systems. HVAC features could modify virus transmission potential. A systematic review following international standards was conducted to comprehensively identify and synthesize research examining the effectiveness of filters within HVAC systems in reducing virus transmission. Twenty-three relevant studies showed that: filtration was associated with decreased transmission; filters removed viruses from the air; increasing filter efficiency (efficiency of particle removal) was associated with decreased transmission, decreased infection risk, and increased viral filtration efficiency (efficiency of virus removal); increasing filter efficiency above MERV 13 was associated with limited benefit in further reduction of virus concentration and infection risk; and filters with the same efficiency rating from different companies showed variable performance. Increasing filter efficiency may mitigate virus transmission; however, improvement may be limited above MERV 13. Adapting HVAC systems to mitigate virus transmission requires a multi-factorial approach and filtration is one factor offering demonstrated potential for decreased transmission.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

The impact of heating, ventilation, and air conditioning design features on the transmission of viruses, including the 2019 novel coronavirus: a systematic review of filtration

Thornton

Fleck

Kroeker

et al. 2021

Preprint

View full text Add to dashboard Cite

show abstract

“…The third-generation, known as next-generation methodologies, is emerging to bridge the gaps of the both previous HRA generations. The last generation employed tools such as Fuzzy logic [26,27], Bayesian network [28], multiple criteria decision making (MCDM), Montecarlo [29], Dempster-Shafer theory [30], are applied in hybrid with already existing techniques to handle a specific challenge.…”

Section: State Of the Artmentioning

confidence: 99%

“…Maniram Kumar et al [35] used Fuzzy logic combining with HEART to overcome the inaccuracy of experts' preferences in assigning the relative strength of EPCs over GTT. Mirzaei Aliabadi [27] proposed a human error analysis composite HEART and Intuitionistic Fuzzy to find HEP in furnace start-ups tasks. Using Fuzzy HEART, Mirzaei Aliabadi et al [36] assess the probability of maintenance error in catalyst replacement of process refinery.…”

Section: State Of the Artmentioning

confidence: 99%

Human reliability analysis in de-energization of power line using HEART in the context of Z-numbers

et al. 2021

View full text Add to dashboard Cite

Investigation reveals that a high percentage of incident causes are ascribed to some forms of human error. To effectively prevent incidents from happening, Human Reliability Analysis (HRA), as a structured way to represent unintentional operator contribution to system reliability, is a critical issue. Human Error Reduction and Assessment Technique (HEART) as a famous HRA technique, provides a straightforward method to estimate probabilities of human error based on the analysis of tasks. However, it faces varying levels of uncertainty in assigning of weights to each error producing condition (EPC), denoted as assessed proportion of affect (APOA), by experts. To overcome this limitation and consider the confidence level (reliability or credibility) of the experts, the current study aimed at proposing a composite HEART methodology for human error probability (HEP) assessment, which integrates HEART and Z-numbers short for, Z-HEART. The applicability and effectiveness of the Z-HEART has been illustrated in the de-energization power line as a case study. Furthermore, a sensitivity analysis is fulfilled to investigate the validity of the proposed methodology. It can be concluded that Z-HEART is feasible for assessing human error, and despite the methodological contributions, it offers many advantages for electricity distribution companies.

show abstract

“…Respiratory aerosols smaller than 5 µm [16,17] released by sneezing can attain a velocity of up to 100 m s −1 , coughing can generate and proliferate the same types of aerosols with velocities of up to 50 m s −1 , talking ones with velocities of 5 m s −1 and normal breathing ones with velocities of 1 m s −1 [18][19][20]. These aerosols can propagate throughout indoor environments [21][22][23], posing a threat to the public. Therefore, chemical surveillance of such microscopic aerosols and their attachment on fomites requires attention beyond standard RT-PCR analysis.…”

Section: Introductionmentioning

confidence: 99%

The Post-COVID-19 Era: Interdisciplinary Demands of Contagion Surveillance Mass Spectrometry for Future Pandemics

et al. 2021

View full text Add to dashboard Cite

Mass spectrometry (MS) can become a potentially useful instrument type for aerosol, droplet and fomite (ADF) contagion surveillance in pandemic outbreaks, such as the ongoing SARS-CoV-2 pandemic. However, this will require development of detection protocols and purposing of instrumentation for in situ environmental contagion surveillance. These approaches include: (1) enhancing biomarker detection by pattern recognition and machine learning; (2) the need for investigating viral degradation induced by environmental factors; (3) representing viral molecular data with multidimensional data transforms, such as van Krevelen diagrams, that can be repurposed to detect viable viruses in environmental samples; and (4) absorbing engineering attributes for developing contagion surveillance MS from those used for astrobiology and chemical, biological, radiological, nuclear (CBRN) monitoring applications. Widespread deployment of such an MS-based contagion surveillance could help identify hot zones, create containment perimeters around them and assist in preventing the endemic-to-pandemic progression of contagious diseases.

show abstract

Modeling aerosol transmission of SARS-CoV-2 in multi-room facility

Cited by 27 publications

References 12 publications

The impact of heating, ventilation, and air conditioning design features on the transmission of viruses, including the 2019 novel coronavirus: a systematic review of filtration

The impact of heating, ventilation, and air conditioning design features on the transmission of viruses, including the 2019 novel coronavirus: a systematic review of filtration

Human reliability analysis in de-energization of power line using HEART in the context of Z-numbers

The Post-COVID-19 Era: Interdisciplinary Demands of Contagion Surveillance Mass Spectrometry for Future Pandemics

Contact Info

Product

Resources

About