volume 40, issue 8, P783-787 2012
DOI: 10.1016/j.jcms.2012.02.011
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Philippe Zanchetta, Nicole Lagarde, Arnaud Uguen, Pascale Marcorelles

Abstract: Skeletal bone losses are mainly filled with autologous graft or artificial materials. Osteoblasts are essential to maintain bone homeostasis and bone repair through a matrix synthesis. We have previously demonstrated that adherence and regenerative matrix composition are fundamental to bone healing, even in critical situations. In this work the critical size defect technique was used to evaluate the systemic activity on bone regeneration of a novel mixture of extracellular polysaccharides. A 5mm diameter hole …

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