“…For instance, a cluster of miRNAs-17-92 is typically expressed in human B-cell lymphomas [16]. Moreover, overexpression of miR-195 during cardiac hypertrophy results in pathological cardiac growth and heart failure, while miR-199a is expressed in cardiomyocytes where it maintains cell size Molecular regulation of miRNAs and potential biomarkers in the progression of hepatic steatosis to NASH future science group Review Wang, Liu, Zou, Hong, Fang & Tong and plays a role in the regulation of cardiac hypertrophy [17]. Such miRNA expression signatures may be able to differentiate human malignancies according to their developmental origin, which has important clinical implications.…”