Di Jia, Shenglan Li, Dali Li, Haipeng Xue, Dan Yang, Ying Liu
Abstract:INTRODUCTION Glioblastoma multiforme (GBM) is one of the most fatal brain tumors with a mean survival rate of 35.7% at one Year, 4.7% at five years, and median overall survival (OS) of 14.6 months [1, 2]. To better understand the impacts of genetic composition of tumor on clinical prognosis, comprehensive genome-wide gene expression collections such as The Cancer Genome Atlas (TCGA) have been established to categorize and discover genomic abnormalities in large cohorts across the world [3, 4]. In the TCGA data…
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