Mindfulness-based supportive therapy on reducing suffering in patients with advanced cancer: randomised controlled trial

Beng, Tan Seng; Chee, Chung Huey; Ngai, Chin Fei; Hii, Siew Lin; Tan, Yi Wen; Ng, Chong Guan; Capelle, David Paul; Zainuddin, Sheriza Izwa; Loh, Ee Chin; Lam, Chee Loong; Chai, Chee-Shee; Ng, Diana Leh-Ching

doi:10.1136/bmjspcare-2021-003349

Cited by 4 publications

(7 citation statements)

References 36 publications

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“…In the literature, we found 2 studies with opposite results. Tan et al, 19 in a RCT with advanced cancer patients, found statistically significant reduction in the overall suffering score in the MBI group compared with the control group (P = .008). On the contrary, Guan et al, 20 compared MBI to “Normal Listening” (control group) in a PALC setting (n = 60) in Malaysia, and found that, although “Mindful-Breathing” was a quick and easy therapy to administer, the reduction of pain did not reach statistical difference between groups.…”

Section: Discussionmentioning

confidence: 94%

Mindfulness on Symptom Control and Quality of Life in Patients in Palliative Care: A Systematic Review

Stadnyk,

Casimiro,

Reis-Pina

2023

Am J Hosp Palliat Care

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Introduction Palliative care is a medical and humanitarian approach that improves the quality of life of patients, and their families, who are facing problems associated with chronic and life-threatening illnesses. Few studies have evaluated the effectiveness of mindfulness-based interventions for terminally ill or incurable patients. The aim of this study was to systematically review the literature on the effect of mindfulness-based interventions on symptom control and quality of life in patients in palliative care. Methods PubMed, Web of Science and Cochrane databases were searched for articles, published between January 2017 and December 2022, in English, including randomized controlled and clinical trials. Participants: terminally ill or incurable patients. Interventions: any mindfulness-based intervention. Comparators: any. Outcomes: symptom control and quality of life. The risk of bias was analysed through Cochrane’s ROB-2 tool. Results Eight studies were included involving 609 patients and 75 dyads patients-spousal caregivers. The overall risk of bias was low to moderate. Mindfulness-based interventions are helpful in managing suffering, anxiety and depressive symptoms, fatigue, insomnia, drowsiness, appetite, and spiritual well-being. Conclusion Mindfulness-based interventions control several symptoms and improve spiritual quality of life in patients in palliative care. Additionally, their informal caregivers also benefit from these interventions. Future trials are crucial to investigate other effects of mindfulness-based interventions, and their long-term benefits, in patients in palliative care.

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Section: Discussionmentioning

confidence: 94%

Mindfulness on Symptom Control and Quality of Life in Patients in Palliative Care: A Systematic Review

Stadnyk,

Casimiro,

Reis-Pina

2023

Am J Hosp Palliat Care

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“…The review identified nine types of death education interventions, including life review intervention ( n = 9), 38–46 meaning-centered psychotherapy ( n = 8), 47–54 dignity therapy ( n = 7), 55–61 Managing Cancer and Living Meaningfully intervention ( n = 7), 62–68 combined psychotherapy interventions ( n = 5), 69–73 cognitive-behavioral therapy ( n = 3), 74–76 narrative therapy ( n = 3), 77–79 general psychosocial intervention ( n = 3), 80–82 and mindfulness interventions ( n = 2). 83,84 The existing death education intervention pertained to facilitate an understanding of life, and most commonly reported topics included life story ( n = 21), heritage ( n = 16), and life accomplishment ( n = 16). The the understanding of death and adaptation to dying was relatively less covered (Supplemental Appendix 2).…”

Section: Resultsmentioning

confidence: 99%

“…The review identified nine types of death education interventions, including life review intervention (n = 9), [38][39][40][41][42][43][44][45][46] meaning-centered psychotherapy (n = 8), [47][48][49][50][51][52][53][54] dignity therapy (n = 7), [55][56][57][58][59][60][61] Managing Cancer and Living Meaningfully intervention (n = 7), [62][63][64][65][66][67][68] combined psychotherapy interventions (n = 5), [69][70][71][72][73] cognitive-behavioral therapy (n = 3), [74][75][76] narrative therapy (n = 3), [77][78][79] general psychosocial intervention (n = 3), [80][81][82] and mindfulness interventions (n = 2). 83,84 The existing death education intervention pertained to facilitate an understanding ...…”

Section: Research Question 1: Types and Components Of Death Education...mentioning

confidence: 99%

Death education interventions for people with advanced diseases and/or their family caregivers: A scoping review

Wang,

Cheung,

Cheng

2024

Palliat Med

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Background: People with life-threatening diseases and their family caregivers confront psychosocial and spiritual issues caused by the persons’ impending death. Reviews of death education interventions in the context of life-threatening diseases are scarce and limited to certain intervention types. Aims: This study aims to ascertain existing evidence on death education interventions for the population of adults with advanced diseases and/or their family caregivers and identify gaps for future research. Design: A scoping review guided by Arksey and O’Malley’s framework. Data sources: Thirteen electronic databases were searched for experimental and qualitative studies on death education interventions for the advanced disease population and/or their family caregivers between 1 January 1960 and 25 October 2023. Results: Nine types of interventions were identified in 47 studies, which included 5 qualitative and 42 experimental designs, half of which were pilot and feasibility trials. Most of the studies focused on people with advanced cancer, and only seven investigated caregivers or families/couples. Death-related outcomes were less likely to be assessed relative to psychological outcomes, spiritual well-being, and quality of life. Life review interventions, cognitive-behavior therapy, narrative therapy, and general psychosocial interventions decreased depression and anxiety, but evidence was limited. Factors contributing to the interventions’ success included intervention content, which enabled the disclosure of personal experience and death concerns comfortably, trained professionals, and connection to family caregivers. Conclusions: This work identified a few potentially effective death education interventions for psychological outcomes for people with advanced cancer or their caregivers. Additional trials are needed to confirm the effectiveness of these interventions.

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“…Several reasons were identified as to why CBT might be less effective in this patient group. For example, stage IV cancer sufferers undergo more intensive medical treatment, they experience more pain, hospitalisation is more common and ultimately participants are more likely to die during the study (Savard et al, 2006;Serfaty et al, 2020). These factors could potentially lead to lack of engagement with CBT, which could result in increased drop-out rates and poorer outcomes.…”

Section: Discussionmentioning

confidence: 99%

“…There is notably less research available that focuses on psychological interventions for metastatic breast cancer, yet this client group experiences high distress levels and low quality of life (Reed et al, 2012). Studies examining the effectiveness of CBT for depression in people with advanced cancer in general found CBT to be less effective than in people with less advanced cancer (Mustafa et al, 2013;Serfaty et al, 2020). For example, the CanTalk study (Serfaty et al, 2020) provided 12 weeks of 1:1 CBT to people with advanced stage breast cancer and found CBT to be ineffective in treating their depression.…”

Section: Discussionmentioning

confidence: 99%

The effectiveness of cognitive behavioural therapy for depression in women with breast cancer: a systematic review and meta-analysis

Wieland,

Melton,

Bastounis

et al. 2024

Behav. Cogn. Psychother.

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Background: Depression is a common co-morbidity in women with breast cancer. Previous systematic reviews investigating cognitive behavioural therapy (CBT) for depression in this population based their conclusions on findings from studies with varying and often limited specificity, quality and/or quantity of CBT within their interventions. Aim: To determine the effectiveness of a specific, well-evidenced CBT protocol for depression in women with breast cancer. Method: Online databases were systematically searched to identify randomised controlled trials (RCTs) testing CBT (aligned to Beck’s protocol) as a treatment for depression in women with breast cancer. Screening, data extraction and risk of bias assessment were independently undertaken by two study authors. Both narrative synthesis and meta-analysis were used to analyse the data. The meta-analysis used a random effects model to compare CBT with non-active/active controls of depression using validated, self-report measures. Results: Six RCTs were included in the narrative synthesis, and five in the meta-analysis (n = 531 participants). Overall, CBT demonstrated an improvement in depression scores in the CBT condition versus active and non-active controls at post-intervention (SMD = –0.93 [95% CI –1.47, –0.40]). Narratively, five out of six RCTs reported statistically significant improvements in depression symptoms for CBT over control conditions for women with breast cancer. Conclusion: CBT aligned to Beck’s protocol for depression appears effective for treating depression in women with breast cancer. However, further research is needed for women with stage IV breast cancer. The clinical recommendation is that therapists utilise Beck’s CBT protocol for depression, whilst considering the complex presentation and adapt their practice accordingly.

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Mindfulness-based supportive therapy on reducing suffering in patients with advanced cancer: randomised controlled trial

Cited by 4 publications

References 36 publications

Mindfulness on Symptom Control and Quality of Life in Patients in Palliative Care: A Systematic Review

Mindfulness on Symptom Control and Quality of Life in Patients in Palliative Care: A Systematic Review

Death education interventions for people with advanced diseases and/or their family caregivers: A scoping review

The effectiveness of cognitive behavioural therapy for depression in women with breast cancer: a systematic review and meta-analysis

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