Mild Cognitive Impairment

Prediction of conversion to Alzheimer’s disease using deep survival analysis of MRI images

“…The estimated probability of Alzheimer’s disease conversion was noticeably higher for the MCI group than for the NC group ( Fig. 2C ), and the timewise change in the MCI group was consistent with a previous report that the typical rate of conversion to Alzheimer’s disease in this group is 10–15% per year ( Petersen et al , 2009 ). In terms of age, the estimated conversion ratio was higher for older patients ( Fig.…”

Prediction of conversion to Alzheimer’s disease using deep survival analysis of MRI images

“…The estimated probability of Alzheimer’s disease conversion was noticeably higher for the MCI group than for the NC group ( Fig. 2C ), and the timewise change in the MCI group was consistent with a previous report that the typical rate of conversion to Alzheimer’s disease in this group is 10–15% per year ( Petersen et al , 2009 ). In terms of age, the estimated conversion ratio was higher for older patients ( Fig.…”

Incidence of dementia in oldest-old with amnestic MCI and other cognitive impairments

“…The 4-fold increase in dementia incidence we found in participants with aMCI compared with participants with normal cognition is of a magnitude similar to the increase found in previous studies with younger elderly participants. [5][6][7][8] We also found a higher dementia incidence in the oldest-old participants with aMCI compared with naMCI, which is consistent with other studies of younger participants. 5,27,28 Participants with OCI had the highest incidence of dementia in our study.…”

“…[5][6][7][8] We also found a higher dementia incidence in the oldest-old participants with aMCI compared with naMCI, which is consistent with other studies of younger participants. 5,27,28 Participants with OCI had the highest incidence of dementia in our study. These participants had a low MMSE score (82%) or functional impairment due to cognition (18%) and were more impaired than either MCI group, although they did not meet DSM-IV criteria for dementia at baseline.…”

The Prevalence of Mild Cognitive Impairment in Diverse Geographical and Ethnocultural Regions: The COSMIC Collaboration

“…We did not find any significant sex differences in MCI prevalence. This is consistent with some previous literature [ 7 , 15 ], but a possibly higher prevalence in men has also been reported [ 18 ]. We did find that the prevalence of MCI increased with age, though the pattern across age groups differed between men and women.…”

“…It is noteworthy that our analysis showed higher prevalence estimates of naMCI to aMCI by a ratio of nearly 2:1, which is consistent with some studies [ 62 , 63 ] but contrary to another [ 7 ]. The literature, however, has not examined naMCI with the same rigor as aMCI, and the common use of the 1999 Mayo Clinic criteria for MCI [ 54 ] conflates aMCI with MCI.…”

Prediction of conversion to Alzheimer’s disease using deep survival analysis of MRI images

“…The estimated probability of Alzheimer’s disease conversion was noticeably higher for the MCI group than for the NC group ( Fig. 2C ), and the timewise change in the MCI group was consistent with a previous report that the typical rate of conversion to Alzheimer’s disease in this group is 10–15% per year ( Petersen et al , 2009 ). In terms of age, the estimated conversion ratio was higher for older patients ( Fig.…”

Incidence of dementia in oldest-old with amnestic MCI and other cognitive impairments

“…The 4-fold increase in dementia incidence we found in participants with aMCI compared with participants with normal cognition is of a magnitude similar to the increase found in previous studies with younger elderly participants. [5][6][7][8] We also found a higher dementia incidence in the oldest-old participants with aMCI compared with naMCI, which is consistent with other studies of younger participants. 5,27,28 Participants with OCI had the highest incidence of dementia in our study.…”

“…[5][6][7][8] We also found a higher dementia incidence in the oldest-old participants with aMCI compared with naMCI, which is consistent with other studies of younger participants. 5,27,28 Participants with OCI had the highest incidence of dementia in our study. These participants had a low MMSE score (82%) or functional impairment due to cognition (18%) and were more impaired than either MCI group, although they did not meet DSM-IV criteria for dementia at baseline.…”

The Prevalence of Mild Cognitive Impairment in Diverse Geographical and Ethnocultural Regions: The COSMIC Collaboration

“…We did not find any significant sex differences in MCI prevalence. This is consistent with some previous literature [ 7 , 15 ], but a possibly higher prevalence in men has also been reported [ 18 ]. We did find that the prevalence of MCI increased with age, though the pattern across age groups differed between men and women.…”

“…It is noteworthy that our analysis showed higher prevalence estimates of naMCI to aMCI by a ratio of nearly 2:1, which is consistent with some studies [ 62 , 63 ] but contrary to another [ 7 ]. The literature, however, has not examined naMCI with the same rigor as aMCI, and the common use of the 1999 Mayo Clinic criteria for MCI [ 54 ] conflates aMCI with MCI.…”

Prediction of conversion to Alzheimer’s disease using deep survival analysis of MRI images

“…The estimated probability of Alzheimer’s disease conversion was noticeably higher for the MCI group than for the NC group ( Fig. 2C ), and the timewise change in the MCI group was consistent with a previous report that the typical rate of conversion to Alzheimer’s disease in this group is 10–15% per year ( Petersen et al , 2009 ). In terms of age, the estimated conversion ratio was higher for older patients ( Fig.…”

Incidence of dementia in oldest-old with amnestic MCI and other cognitive impairments

“…The 4-fold increase in dementia incidence we found in participants with aMCI compared with participants with normal cognition is of a magnitude similar to the increase found in previous studies with younger elderly participants. [5][6][7][8] We also found a higher dementia incidence in the oldest-old participants with aMCI compared with naMCI, which is consistent with other studies of younger participants. 5,27,28 Participants with OCI had the highest incidence of dementia in our study.…”

“…[5][6][7][8] We also found a higher dementia incidence in the oldest-old participants with aMCI compared with naMCI, which is consistent with other studies of younger participants. 5,27,28 Participants with OCI had the highest incidence of dementia in our study. These participants had a low MMSE score (82%) or functional impairment due to cognition (18%) and were more impaired than either MCI group, although they did not meet DSM-IV criteria for dementia at baseline.…”

The Prevalence of Mild Cognitive Impairment in Diverse Geographical and Ethnocultural Regions: The COSMIC Collaboration

“…We did not find any significant sex differences in MCI prevalence. This is consistent with some previous literature [ 7 , 15 ], but a possibly higher prevalence in men has also been reported [ 18 ]. We did find that the prevalence of MCI increased with age, though the pattern across age groups differed between men and women.…”

“…It is noteworthy that our analysis showed higher prevalence estimates of naMCI to aMCI by a ratio of nearly 2:1, which is consistent with some studies [ 62 , 63 ] but contrary to another [ 7 ]. The literature, however, has not examined naMCI with the same rigor as aMCI, and the common use of the 1999 Mayo Clinic criteria for MCI [ 54 ] conflates aMCI with MCI.…”