2008
DOI: 10.1590/s0102-695x2008000500019
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Abstract: RESUMO:Apesar da atividade farmacológica de Mikania glomerata Spreng. ser conhecida desde longa data, existem poucos estudos visando a preparação de produtos padronizados que garantam uma produção uniforme, doses efi cazes e estabilidade. Nesse trabalho, foram realizados ensaios objetivando a otimização do processo extrativo; tratamento da droga vegetal para o preparo de tinturas; determinação da melhor forma de estocagem e otimização da preparação da forma farmacêutica (xarope).Unitermos: Mikania glomerata, A… Show more

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Cited by 19 publications
(19 citation statements)
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“…Coumarin is a heterocyclic, aromatic, organic compound found in numerous plant species with pharmacological potential such as Amburana cearensis, Mikania glomerata and Hybanthus ipecacuanha (Leal et al, 2000;Rocha et al, 2008). Due to its capacity to potentiate the proteolytic activity of macrophages, CM has been indicated for the treatment of patients with lymphoedema (Clodius & Piller, 1978), while coumarinic derivatives, such as UMB, possess numerous specific pharmacological properties including antiinflammatory , spasmolytic (Lino et al, 1997), hypoglycaemic and hypolipidemic activities (Ramesh & Pugalendi, 2005).…”
Section: Introductionmentioning
confidence: 99%
“…Coumarin is a heterocyclic, aromatic, organic compound found in numerous plant species with pharmacological potential such as Amburana cearensis, Mikania glomerata and Hybanthus ipecacuanha (Leal et al, 2000;Rocha et al, 2008). Due to its capacity to potentiate the proteolytic activity of macrophages, CM has been indicated for the treatment of patients with lymphoedema (Clodius & Piller, 1978), while coumarinic derivatives, such as UMB, possess numerous specific pharmacological properties including antiinflammatory , spasmolytic (Lino et al, 1997), hypoglycaemic and hypolipidemic activities (Ramesh & Pugalendi, 2005).…”
Section: Introductionmentioning
confidence: 99%
“…ex Baker, conhecidas popularmente como guaco. M. glomerata consta da 1ª edição da farmacopéia brasileira e da RE nº 89, que se refere à lista de registro simplificado de fitoterápicos (Pharmacopéia dos Estados Unidos do Brasil, 1926;Brasil, 2004;Brandão et al, 2006Brandão et al, , 2008Carvalho et al, 2008;Rocha et al, 2008), e M. laevigata encontrase descrita no sexto fascículo da farmacopéia brasileira 4ª edição (Farmacopéia Brasileira, 2005;Brandão et al, 2006Brandão et al, , 2008. A cumarina (1,2-benzopirona) é o marcador químico descrito para as duas espécies (Brasil, 2004;Farmacopéia Brasileira, 2005;Silva et al, 2008).…”
Section: Introductionunclassified
“…The technological development of research on pharmaceutical forms containing herbal materials has expanded over recent decades and contributed to innovation in the pharmaceutical sector (Bassani, González, Petrovick, 2005;Calixto, 2005;Rocha et al, 2008;Araújo-Júnior et al, 2013;Beringhs et al, 2013;Couto et al, 2013;Klein et al, 2013;Quintão et al, 2013).…”
Section: Introductionmentioning
confidence: 99%