2010
DOI: 10.1590/s0004-282x2010000500018
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Abstract: Objective: It is a consensus that most unruptured intracranial aneurysms (UIA) can be treated with acceptably low morbidity. However, some studies recently reported postoperative cognitive impairment, suggesting that it could be attributable to surgical damage. Our goal is to evaluate cognitive function before and after microsurgical clipping in patients with UIA. Method: A consecutive series of 40 patients who underwent microsurgical clipping for UIA were studied. The cognitive assessment (Mini Mental State E… Show more

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Cited by 24 publications
(13 citation statements)
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“…Subsequent small, prospective, single-center series examining cognitive function before and after clipping have not borne out the same conclusion, demonstrating no cognitive dysfunction on Mini-Mental State Examination at 1 month after surgery. 210,211 There have been contradictory results in series that used more comprehensive neuropsychological batteries. 210,212,213 Nonetheless, it appears that standard outcomes instruments such as the mRS and the Glasgow Outcome Scale do not correlate with results of the Mini-Mental State Examination after aneurysm surgery, 214 and thus, the incorporation of cognitive assessment of patients can provide additional useful outcomes information.…”
Section: Surgical Clipping Outcomesmentioning
confidence: 99%
“…Subsequent small, prospective, single-center series examining cognitive function before and after clipping have not borne out the same conclusion, demonstrating no cognitive dysfunction on Mini-Mental State Examination at 1 month after surgery. 210,211 There have been contradictory results in series that used more comprehensive neuropsychological batteries. 210,212,213 Nonetheless, it appears that standard outcomes instruments such as the mRS and the Glasgow Outcome Scale do not correlate with results of the Mini-Mental State Examination after aneurysm surgery, 214 and thus, the incorporation of cognitive assessment of patients can provide additional useful outcomes information.…”
Section: Surgical Clipping Outcomesmentioning
confidence: 99%
“…Along similar lines, surgical treatment has produced low rates of morbidity and mortality in patients with unruptured aneurysms in expert hands. 5,108,109,123,141 Tuffiash et al 141 demonstrated no cognitive effects of craniotomy for unruptured aneurysms. Furthermore, the unparalleled team of Dr. Charles Drake and colleagues was able to clip unruptured basilar bifurcation aneurysms smaller than 12.5 mm in diameter with a 3.6% risk of poor outcome and no mortality.…”
mentioning
confidence: 99%
“…Neither of the studies using the MMSE 8,27 found any difference in general cognition between pre-and posttreatment phases. It is possible that the MMSE as a test of general cognitive ability might not be sensitive enough to detect the subtle deficits associated with UIA.…”
Section: Discussionmentioning
confidence: 88%
“…While 4 of the studies 14,25,27,28 explicitly state that cognitively impaired patients at baseline were excluded, the other 3 make no such claims. While this could represent a simpler problem with incomprehensive manuscript preparation, it nevertheless introduces uncertainty into their results.…”
Section: Discussionmentioning
confidence: 99%