Microstructure, mechanical properties, and in vitro biocompatibility of spark plasma sintered hydroxyapatite–aluminum oxide–carbon nanotube composite

Kalmodia, Sushma; Goenka, Shilpi; Laha, Tapas; Lahiri, Debrupa; Basu, Bikramjit; Balani, Kantesh

doi:10.1016/j.msec.2010.06.009

Cited by 64 publications

(36 citation statements)

References 37 publications

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“…On the other hand, the highest values of microhardness and lower values of flexural strength were observed in the group of pure alumina with the greatest grain sizes (>1 µ); this aspect is relevant for the composites studied. Kalmodia et al 19) mention that some ceramic composite materials exhibit the ability to promote cell adhesion and proliferation on their surface when alumina is added to compositions, but in our results, the cell viability and alumina content ratio was observed as irrelevant, not finding important differences between the different ceramics studied. The innovation with new ceramic materials for biomedical applications requires yet to be tested in order to prove they are suitable for such purpose 20) .…”

Section: Discussioncontrasting

confidence: 81%

Synthesis, biocompatibility and mechanical properties of ZrO2-Al2O3 ceramics composites

et al. 2016

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This study evaluated cell viability, microhardness and flexural strength of two ceramic composites systems (ZA and AZ), pure alumina and zirconia. There were prepared homogeneous mixtures of 78wt%Al2O3+20wt%3Y-TZP+2wt%Al2O3w (AZ) and 80wt%3Y-TZP+18wt%Al2O3+2wt%Al2O3w (ZA), as well as 3Y-TZP (Z), pure Al2O3 (A) and commercial monolithic 3Y-TZP (Zc). Also mouse fibroblast cells 3T3-L1 and a MTT test was carried out at 24, 48 and 72 h. The surfaces were observed with SEM and the microhardness and three-point flexural strength values were estimated. The absolute microhardness values were: A>AZ>Z>Zc>ZA. Flexural strength of Zc, Z, and ZA were around double than AZ and A. All groups showed high biocompatibility trough cell viability values at 24, 48 and 72 h. Factors like grain shape, grain size and homogeneous or heterogeneous grain distributions may play an important role in physical, mechanical and biological properties of the ceramic composites.

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Section: Discussioncontrasting

confidence: 81%

Synthesis, biocompatibility and mechanical properties of ZrO2-Al2O3 ceramics composites

et al. 2016

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“…915 For example, HA was combined with Bioglass ® (Novabone Products, Alachua, FL) 916,917 and with other glasses 918 to form glass-ceramic biocomposites. Other reinforcement materials for calcium orthophosphates are differentiated either by shape of the fillers, namely, particles, 919,920 More complicated formulations, such as HA/aluminum oxide/ carbon nanotubes, 1058 have been developed as well. All these materials have been added to calcium orthophosphate bioceramics to improve their reliability.…”

Section: ©2 0 1 1 L a N D E S B I O S C I E N C E D O N O T D I S Tmentioning

confidence: 99%

Biocomposites and hybrid biomaterials based on calcium orthophosphates

Dorozhkin¹

2011

Biomatter

152

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“…It is a most used implant for tissue implantation due to its similarity with apatite in human skeletal system, bone and teeth in terms of the chemical composition (Ca/P ratio of 1.67) and crystal structure [3]. HAP in different forms (powder, fiber, sintered) exhibited the excellent biocompatibility [4,5]. Sintered HAP may be an ideal candidate for orthopaedic and dental implants.…”

Section: Introductionmentioning

confidence: 99%