DOI: 10.1007/978-1-4939-7435-1_7
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Abstract: Gene regulatory network that determines the cellular functions exhibits stochastic fluctuations, or "noise," in different layers. Noise has begun to be appreciated for many previously unrecognized functions in important cellular activities. In fact, molecular noise is unavoidable in both microbial and eukaryotic cells, the feedback system is established evolutionally to reduce noise or optimize the noise for cellular homeostasis. The small noncoding RNAs, particularly, microNRAs, post-transcriptionally and neg…

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