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Cited by 55 publications
(43 citation statements)
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“…These results are opposed to others previously reported in obese [30, 31] and type 2 diabetic individuals [32], in whom downregulation of miR-223 was found. Another study, however, found that levels were unchanged in diabetic subjects [33].…”
Section: Discussioncontrasting
confidence: 99%
“…These results are opposed to others previously reported in obese [30, 31] and type 2 diabetic individuals [32], in whom downregulation of miR-223 was found. Another study, however, found that levels were unchanged in diabetic subjects [33].…”
Section: Discussioncontrasting
confidence: 99%
“…The regulatory effects of miRNAs on adipose tissue metabolism are mediated via regulation of cell differentiation, proliferation, apoptosis and appetite (Chen et al, 2013). miRNAs that have been connected to insulin resistance, diabetes or obesity include miR-21, miR-221/222, miR-146b, miR-33a and -b, miR-103, miR-107, miR-192* and miR-143 (Nakanishi et al, 2009;Xie et al, 2009;Rottiers and Näär, 2012;Kilic et al, 2015;Mysore et al, 2016). miR-378, -326, −193b, −126, −26a -and a number of others -regulate adiponectin (AdipoQ), which is an important regulator and marker of adipogenesis (Ishida et al, 2014;Santovito et al, 2014;Belarbi et al, 2015).…”
Section: Introductionmentioning
confidence: 99%
“…miR-143 and miR-223 levels were significantly lower in the morbidly obese group and obese group than the control group (normal BMI or overweight). Obesity leads to alterations in miRNA expression, and miRNA-143 and miR-223s can be used as biomarkers for the metabolic changes in obesity (Kilic et al, 2015). Studies have shown that miR-NAs may be involved in the regulation of mitosis and gene expression during spermatogenesis.…”
Section: Discussionmentioning
confidence: 99%