Microparticles, microcapsules and microspheres: A review of recent developments and prospects for oral delivery of insulin

Biocatalytic reversible control of the stiffness of DNA-modified responsive hydrogels: applications in shape-memory, self-healing and autonomous controlled release of insulin

“…In fact, different previous studies have discussed the possibilities of developing articial pancreas systems for the autonomous switchable release of insulin. [60][61][62] Nonetheless, these systems operated at irrelevant concentrations of glucose or the switching ON/OFF release time-intervals of insulin were inappropriate for controlling diabetes. The formation of the toxic H 2 O 2 , a ROS-generated product, accompanying the aerobic GOx-catalyzed oxidation of glucose, needs to be addressed to support the potential utility of the system.…”

Cyclodextrin modified niosomes to encapsulate hydrophilic compounds

“…For this reason, different strategies have been proposed, based on the use of delivery devices such as microspheres, microemulsions, nanoparticles, microcapsules, implantable pumps, and vesicular systems among others. [1][2][3][4][5][6][7] There are several advantages of using active compound delivery systems, for example, to protect drugs from a hostile environment (enzymes, pH, heat, air, light, moisture) or to improve poor aqueous solubility of the active agents that limits bioavailability and efficiency in the action site. 8,9 Among the promising drug targeting vehicles are vesicles.…”

Swelling Performance Studies of Acrylamide/Potassium 3-Sulfopropyl Methacrylate/Sodium Alginate/Bentonite Biohybrid Sorbent Hydrogels in Binary Mixtures of Water-Solvent

“…in cm2 •s −1 , r is the radius of a cylindrical polymer sample, n is the diffusional exponent and k is a constant incorporating characteristic of the macro-molecular network system and the penetrant. The values of diffusion coefficient determined for the hydrogels are listed in Tables 3-5.…”