Microorganisms and antibiotic susceptibilities isolated from urine cultures

Abstract

Objectives: Urinary tract infection (UTI) is the second most common cause of infection among all infectious diseases at hospitals. Antibiogram results are needed to maintain treatment in patients with suspected UTI. However, empirical antibiotic treatment is initiated in patients since it takes time to obtain the results of antibiograms. The aim of this study was to evaluate the urine culture and antibiogram results of patients who were admitted to our hospital with suspected UTI and compare the results with other studies. Methods: Urine cultures requested from the hospital information system database between January of 2018 and 2019 were analyzed. Microorganism-positive urine samples and antibiogram results were evaluated and included in the study. Results: Of the patients, 748 (61.8%) were female and 463 (38.2%) were male. The average age of all patients was 44.9 years. Escherichia coli was the most frequently isolated microorganisms from urine cultures (n = 828, 68.4%). Among all microorganism-positive urine samples, antibiotic resistance against Cefalexin, Fusidic acid, Ampicillin, Erythromycin, Levofloxacin, Cefuroxime Axetil, Trimethoprim/ Sulfamethoxazole, Ceftriaxone and Ciprofloxacin was 83.9%, 68.4%, 61.8%, 44.7%, 42.7%, 36.4%, 30%, 28.6% and 26.7%, respectively. Conclusions: High resistance to Cefalexin, Ampicillin, Cefuroxime, Axetil, Trimethoprim/ Sulfamethoxazole, Ceftriaxone and Ciprofloxacin, which are often preferred in empirical antibiotic selection, has been found. We believe that empirical antibiotic selection should not be overlooked in cases of UTI. Our study may help clinicians use appropriate antibiotics for the clinical management of UTIs.

Susceptibility and Synergistic Effects of Guava Plant Extract and Antimicrobial Drugs on Escherichia coli

“…The current study included 180 urine samples from UTI patients, out of which growth of organisms was observed in a total of 93 samples. The most significant growth was of the organism E. coli, found in 30 samples (32.25%), followed by Candida albicans in 17 samples ( [13]. In the present study, the incidence of E. coli was 51.66%, which was quite similar to the findings reported by Hamza et al, but lower than the incidence reported by Gul and Gurbuz, who found E. coli in 68.4% of 1211 urine samples [12,13].…”

“…Another study conducted by Gul and Gurbuz involved 1211 urine samples, in which the organisms isolated were 0.17% Acinetobacter , 0.58% of Acinetobacter baumannii , 0.08% of Alcaligenes faecalis , 0.08% of Burkholderia cepacia , 1.24% of Candida albicans , 0.08% of Candida famata , 0.17% of Candida kefyr , 0.08% of Candida krusei , 0.25% of Candida spherica , 0.25% of Candida tropicalis , 0.17% of Citrobacter freundii , 0.25% of Citrobacter koseri , 0.08% of Enterobacter aerogenes , 0.74% of Enterobacter cloacae , 0.33% of Enterococcus species, 4.5% of Enterococcus faecalis , 0.74% of Enterococcus faecium , 68.4% of Escherichia coli , 2.8% of Klebsiella species, 0.5% of Klebsiella oxytoca , 7.2% of Klebsiella pneumoniae , 0.25% of Morganella morganii , 0.33% of Proteus species, 1.73% of Proteus mirabilis , 0.33% of Providencia rettgeri , 1.2% of Pseudomonas aeruginosa 10.08% of Salmonella species, 0.17% of Serratia fonticola , 0.17% of Serratia liquefaciens , 0.08% of Serratia marcescens , 0.08% of Shigella sonnei , 0.33% of Staphylococcus aureus , 1.9% of Staphylococcus epidermidis , 0.25% of Staphylococcus haemolyticus , 0.08% of Staphylococcus hominis , 0.5% of Staphylococcus saprophyticus , 0.08% of Staphylococcus warneri , 0.17% of Streptococcus species, 15% of Streptococcus agalactiae , 0.08% of Streptococcus constellatus , 0.17% of Streptococcus dysgalactiae , 0.25% of Streptococcus mitis , 0.08% of Streptococcus salivarius , and 0.08% of Streptococcus sanguinis [ 13 ]. In the present study, the incidence of E. coli was 51.66%, which was quite similar to the findings reported by Hamza et al, but lower than the incidence reported by Gul and Gurbuz, who found E. coli in 68.4% of 1211 urine samples [ 12 , 13 ].…”

Antimicrobial susceptibility of bacteria isolated from urine cultures in Southern Turkey

“…Similar high resistance rates, especially for E. coli , have been reported by other studies in our country. [14,20,26] These results emphasize the importance of antibiotic stewardship programs. Since the national surveillance and infection control programs started in Turkey in 2005, health care-associated infection rates have declined over the past 10 years.…”

Etiological spectrum and antimicrobial resistance of the most frequently isolated pathogens, associated with urinary tract infections in ambulatory patients

“…Recent research from Romania shows 12.6% cefuroxime resistance in urine isolates of E. coli (12). Other neighboring countries report 36% resistance in 2018 (13).…”