Microglia as a Possible Alternative Therapeutic for Dementia
Jessica Sarahi Alavez-Rubio,
Teresa Juarez-Cedillo
Abstract:Dementia is a syndrome in which there is deterioration in memory, behavior, and the ability to perform everyday activities. Alzheimer’s disease and vascular dementia are the most common forms of dementia. There is evidence supporting the hypothesis that inflammatory and immune mechanisms are involved in dementia. Microglia, the resident macrophage tissues in the central nervous system, play a significant role in neuroinflammation and play an important role in amyloid-β clearance in the brain, and impaired micr… Show more
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