Microcystic Adnexal Carcinoma.

Periocular Microcystic Adnexal Carcinoma: A Case Report and a Major Review

“…Review of the literature identified 92 patients fulfilling the inclusion criteria for this study in addition to our current patient, for a total of 93 patients with MAC. 2,3,5,8,9,11–69 Patient demographics and presenting characteristics are summarized in Table 1.…”

“…Information on the duration of follow-up was available on 64 of 93 patients (69%). 2,3,5,8,9,11–16,18,20–22,24–33,36–51,53–55,57–59,61–69 The average total period of observation from the time of initial presentation to the final documented care was 8 years (median 5, range 0.2–70 years), and the average follow-up after last documented treatment was 3 years (median 2, range 0.2–20 years). Follow-up information was available on 87 of 93 (94%) patients.…”

“…There was no appreciable side predilection (right, 41/77, 53% vs. left, 36/77, 47%). Eighty-six of 93 (92%) tumors originated in the periocular skin, most commonly in the eyebrow (26/86, 30%) [12][13][14]17,18,20,22,23,[25][26][27]29,30,36,37,43,47,48,53,[59][60][61]67 followed by the lower eyelid (20/86, 23%). 2,8,11,13,32,33,35,39,40,49,54,56,58,59,62 Fifteen of 86 (17%) tumors involved more than 1 region.…”

“…8,19,31,50,[64][65][66] Biopsy/debulking without definitive resection was performed in 9 (10%) patients. 2,8,24,29,30,40,55,61 Regional lymph node dissection was undertaken in 4 (4%) patients. 31,56,59,66 Eight (9%) patients underwent adjuvant radiotherapy.…”

“…Information on the duration of follow-up was available on 64 of 93 patients (69%). 2,3,5,8,9,[11][12][13][14][15][16]18,[20][21][22][24][25][26][27][28][29][30][31][32][33][36][37][38][39][40][41][42][43][44][45][46][47][48][49][50][51][53][54][55][57][58][59][61][62][63][64][65][66]…”