Microbiology of Acute Otitis Externa

Roland, Peter S.; Stroman, David W.

doi:10.1097/00005537-200207000-00005

Cited by 223 publications

(153 citation statements)

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“…The isolated strain proved to be resistant only to penicillin and fosfomycin, the latter feature being considered a helpful presumptive test for the identification of S. caprae [2,14]. The susceptibility pattern of the isolate in the current case turned out to be similar to those reported by Vandenesch et al [14], Roland et al [9] and Kini et al [4]. However, meticillin-resistant S. caprae strains have also been reported [7,15].…”

Section: Discussionsupporting

confidence: 79%

“…Recently, meningitis following the infection of an intraspinal device and central lineassociated bacteraemia have been described [6,7]. One case of mastoiditis and cases of acute otitis externa have also been documented [8,9]. Reported human S. caprae infections have been acquired nosocomially following the administration of antibiotics [2,3].…”

Section: Introductionmentioning

confidence: 99%

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First report of a <i>Staphylococcus caprae</i> isolated from middle ear fluid of an infant with recurrent acute otitis media

Mazur

Żychowski

Juda

et al. 2017

Ann Agric Environ Med.

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Staphylococcus caprae was originally isolated from goat milk. This uncommon coagulase-negative staphylococcus, usually associated with animals, has only infrequently been detected in human clinical specimens. Its association with acute otitis media has not been demonstrated so far. The study reports the first isolation of S. caprae from the middle ear fluid of a 12-month-old infant with recurrent, bilateral acute otitis media. Biochemical traits and susceptibility pattern of the isolated strain are also presented.

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Section: Discussionsupporting

confidence: 79%

Section: Introductionmentioning

confidence: 99%

First report of a <i>Staphylococcus caprae</i> isolated from middle ear fluid of an infant with recurrent acute otitis media

Mazur

Żychowski

Juda

et al. 2017

Ann Agric Environ Med.

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“…The most frequently isolated microorganism in cases of AOE is Pseudomonas aeruginosa, which has gram-negative properties and reproduces easily on a moist base [3] . Topical treatment is generally used in the treatment of AOE.…”

Section: Introductionmentioning

confidence: 99%

The Role of Topical Thymoquinone in the Treatment of Acute Otitis Externa; an Experimental Study in Rats

et al. 2018

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OBJECTIVE:The aim of this experimental study was to compare the dose-related effect of topical thymoquinone (TQ) with other topical agents used in the management of acute otitis externa (AOE) in a rat model. MATERIALS and METHODS:Forty-eight male Wistar albino rats were divided into six groups each with eight rats per group. Group I was the control group with no external otitis, whereas external otitis were created in the other five groups (study groups). Dexamethasone, 0.1% TQ, 0.4% TQ, ciprofloxacin, and 0.9% saline (NaCl) drops was applied once daily in Groups II-VI, respectively. The treatment was administered regularly for 10 days. Pathologic and microbiologic evaluation were performed. Pathologically, the thicknesses of the stroma and the epithelium in the external auditory canal (EAC) were measured using an occulometer. Edema in the stroma, density of inflammatory cells and blood vessels, presence of fibroblasts, and changes in collagen fibers in the EAC were evaluated in five different areas to obtain the area of highest concentration and classified into four grades (0=no change, 1=mild, 2=moderate, 3=severe). RESULTS:The higher concentration of TQ (0.4%) was more effective than dexamethasone and 0.1% TQ with respect to antibacterial and the anti-inflammatory properties. CONCLUSION:TQ, particularly at a concentration of 0.4%, may be considered for topical application alone in the treatment of AOE, without any requirement for a combined treatment.

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“…OE can be categorized as localized or diffuse, if it persists for more than 6 months, it is considered 3 chronic and is more commonly bilateral. The predisposing factors for O s Externa include high humidity, and loss of the canal's protec ve coa ng of cerumen, eczema, glandular 4 obstruc on and local lipid/acid disbalance. It is also commonly seen in swimmers, par cularly in the summer 5,6 months.…”

Section: Introductionmentioning

confidence: 99%

A Comparative Study on Efficacy of Polymyxin B, Neomycin and Polymyxin B, Neomycin, Hydrocortisone in the Treatment of Otitis Externa at Nepal Medical College and Teaching Hospital, Kathmandu

Gupta¹,

Aryal

2017

Birat J. Health Sci.

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IntroductionAcute otitis externa (AOE) is a common but preventable ear condition. Tenderness with movement of the tragus or pinna is a classic feature of otitis Externa. Polymyxin B, neomycin, hydrocortisone preparations are the choice for first-line therapy when the tympanic membrane is intact. This study atiempted to compare the efficacy of polymyxin B, neomycin and polymyxin B, neomycin, hydrocortisone in the treatment of otitis Externa.ObjectiveTo compare the efficacy of polymyxin B, neomycin and polymyxin B, neomycin, hydrocortisone in the treatment of otitis Externa.MethodologyTo evaluate the efficacy of polymyxin B, neomycin and polymyxin B, neomycin, hydrocortisone in the treatment of otitis Externa, a hospital based, randomized, prospective study was conducted in Nepal Medical College and Teaching Hospital (NMCTH), Atiarkhel, Kathmandu from August 2012 to May 2014. 70 outpatients suffering from otitis Externa who met the inclusion and exclusion criteria were included. Patients were randomized into group A and group B with lotiery system. Odd number patients were included in group A and even number patients in group B. Group A patients received pack soaked with ribbon gauge in polymyxin B, neomycin ointment and Group B patients received pack soaked with ribbon gauge in polymyxin B, neomycin, hydrocortisone ointment. The patients were called for follow up after 48 hours and 96 hours to assess the improvement on the basis of tragal and circumduction tenderness either present or absent (present 1 or absent 2). A decrease in the clinical signs and symptoms (i.e. tragal and circumduc_on tenderness) was noted. Absence of pain was considered as clinically cured.ResultsIn comparison to polymyxin B, neomycin group, hydrocortisone group exhibited statistically significant effectiveness after 48 hours of treatment (p<0.05), but in cure rates after 96 hours, no statistical significant difference was observed between two groups (p>0.05).ConclusionPolymyxin B, neomycin, hydrocortisone group showed higher and faster cure rates than polymyxin B, neomycin group in the treatment of otitis Externa at 48 hours follow up. Birat Journal of Health SciencesVol.2/No.1/Issue 2/ Jan - April 2017, Page: 162-167

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Microbiology of Acute Otitis Externa

Cited by 223 publications

References 10 publications

First report of a <i>Staphylococcus caprae</i> isolated from middle ear fluid of an infant with recurrent acute otitis media

First report of a <i>Staphylococcus caprae</i> isolated from middle ear fluid of an infant with recurrent acute otitis media

The Role of Topical Thymoquinone in the Treatment of Acute Otitis Externa; an Experimental Study in Rats

A Comparative Study on Efficacy of Polymyxin B, Neomycin and Polymyxin B, Neomycin, Hydrocortisone in the Treatment of Otitis Externa at Nepal Medical College and Teaching Hospital, Kathmandu

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