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Cited by 2 publications
(2 citation statements)
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References 7 publications
(13 reference statements)
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“…Recent research has established that birth by C-section can result in different pattern of behaviour in humans [6][7][8] and in animals [9][10][11]. Recent discoveries point to a pivotal role for OXT in regulating general well-being through its influence on neuroimmune-endocrine pathways [57]. Here we demonstrate that pharmacological manipulation of the OXT system during the early postnatal period (P1-P5) improves social and anxiety-like behaviours, as well as the immune response later in life in the C-section mice model.…”
Section: Discussionmentioning
confidence: 99%
“…Recent research has established that birth by C-section can result in different pattern of behaviour in humans [6][7][8] and in animals [9][10][11]. Recent discoveries point to a pivotal role for OXT in regulating general well-being through its influence on neuroimmune-endocrine pathways [57]. Here we demonstrate that pharmacological manipulation of the OXT system during the early postnatal period (P1-P5) improves social and anxiety-like behaviours, as well as the immune response later in life in the C-section mice model.…”
Section: Discussionmentioning
confidence: 99%
“…Another study by Varian et al (2016) showed that microbe monotherapy was sufficient to increase thymus gland size, inhibit intestinal polyp formation, and increase lifespan in mouse models [18]. The proposed immune mechanisms involved microbial up-regulation of transcription factor Forkhead box protein N1 (FoxN1), the protein that is entirely lacking in athymic nude mice rendering them without T lymphocytes and as a result highly permissive to cancer growth [18,19].…”
mentioning
confidence: 99%