“…CG methylation frequently occurs in gene body regions, whereas CHG and CHH methylation are mostly found in TEs and other repetitive sequences (Cokus et al, 2008;Lister et al, 2008;Schmitz et al, 2011;Rambani et al, 2015;Yong-Villalobos et al, 2015;Zhang et al, 2015;Kawakatsu et al, 2016). While the functional role of gene body methylation is not fully understood, it has been suggested that methylation in the gene body may fine-tune transcriptional activity, regulate alternative splicing efficiency, and inhibit aberrant transcription of long transcripts (Zilberman et al, 2007;Luco et al, 2010;Maunakea et al, 2010;Regulski et al, 2013;Rambani et al, 2015).…”