Abstract:BackgroundAberrant Septin9 methylation in cervical cancer has been rarely studied. In this study we aimed to identify its diagnostic value of cervical cancer in cervical scrapings, and its predictive potential in plasma for pelvic nodal metastasis of cervical cancer.MethodsThe statuses of methylated Septin9 in fresh cervical lesions were first evaluated by using quantitative methylation-specific PCR(qMS-PCR). Subsequently 248 samples of cervical scrapings were collected to explore Septin9 methylation in differ… Show more
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