Methodological issues for population-based research into dementia in developing countries. A position paper from the 10/66 Dementia Research Group

Fibrilação atrial e demência: resultados do São Paulo ageing & health study

“…In low-income populations, education and cultural differences may also influence the results 22 . In this population-based study, we used a validated algorithm specifically developed for dementia diagnosis in low-and middle-income populations based on DSM-IV criteria that consists of multiple diagnostic tools and is corroborated by earlier studies 13 .…”

Can Dementia Be Prevented? Brain Aging in a Population-Based Context

“…One barrier, among many, to doing dementia research in developing countries or across cultural groups is the lack of relatively unbiased screening and assessment instruments that are feasible for use in settings with minimal resources and populations with low literacy levels. A methodology for ascertaining dementia in developing countries, which may make such research more feasible in the future, has been proposed by the 10/66 group (106,107). A consistent pattern emerges from comparison of dementia incidence rates across populations: Rates appear to be lower in developing countries compared to developed countries.…”

Epidemiology of dementia in Central Africa (EPIDEMCA): protocol for a multicentre population-based study in rural and urban areas of the Central African Republic and the Republic of Congo

“…However, previous 2-phase studies in Benin, Central African Republic, Congo and Tanzania (Guerchet et al 2009; Paraïso et al 2011; Guerchet et al 2010; Paddick et al 2013) showed lower attrition rates than described by the 10/66 Dementia Research Group (Prince 2000), reassuring us about the feasibility and the robustness of two-phase epidemiological surveys in SSA. The threshold used to select participants for the second phase and clinical assessment was furthermore defined according to sensitivity and specificity found in previous studies carried out in the same elderly populations.…”