2003
DOI: 10.1076/orbi.22.1.15.14007
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Metastic tumors of the orbit: A retrospective study

Abstract: Orbital metastases remain an unfavorable prognostic factor, but the diagnosis and treatment are still important in order to prevent loss of vision and improve the patient's quality of life. As previous studies have shown, the overall survival rate is still as limited as nearly half a century ago.

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Cited by 46 publications
(29 citation statements)
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“…With orbital metastases from TCC, there is a poorer prognosis than with common metastatic tumors to the orbit, such as from the breast. 1 The patient in the present case was treated with a combination of radiation therapy and systemic chemotherapy with methotrexate, epirubicin, and cisplatin, and was the second longest surviving patient among all reported cases.…”
Section: Discussionmentioning
confidence: 89%
“…With orbital metastases from TCC, there is a poorer prognosis than with common metastatic tumors to the orbit, such as from the breast. 1 The patient in the present case was treated with a combination of radiation therapy and systemic chemotherapy with methotrexate, epirubicin, and cisplatin, and was the second longest surviving patient among all reported cases.…”
Section: Discussionmentioning
confidence: 89%
“…In yet another series of 21 cases with orbital metastasis, we observe that the latter originated in the mammary gland in 67% of cases and in skin melanoma in 14% of cases (15). In another study of 20 cases, the origin was the mammary gland in 40% of cases, prostate in 10% and lung in 10% (16). A bibliographical review published in 1990 shows results obtained for the origin of metastases: 42% originated in the mammary gland, 11% in lungs, 8,3% in the prostate, 5.2% are melanomas and 3.2% in kidneys.…”
Section: Discussionmentioning
confidence: 91%
“…Asides from these spots, orbital metastasis has also been found in the bladder (16,21), intestinal tract and throat (16,22,23), malignant solitary fibrous tumor in thorax (24), neuroendocrine tumor (25), dermatofibrosarcoma (26), renal medullar carcinoma (27), pleural mesothelioma (28), perineal alveolar rhabdomyosarcoma (29), pelvic teleangietatic osteosarcoma (30), spermatic cord leiomyosarcoma (31), ganglioneuroblastoma of the adrenal (32), forearm synovial sarcoma (33), pancreatic islets (34), hepatocellular liver carcinoma (35) and cervix (36) among others. In our 4-case series, location of the primary tumor matches the most frequently reported originating spots.…”
Section: Discussionmentioning
confidence: 99%
“…The most common neoplastic lesions in the cavernous sinus result from direct invasion by parasellar lesions (eg, pituitary adenoma, craniopharyngioma, meningioma, chordoma), perineural spread fr om hea d and neck m alig nancies, or hematogenous spread from distant cancers (eg, breast, prostate, lung, lymphoma) [3,22]. Tumors that commonly invade the orbit include meningiomas, metastatic tumors (eg, breast, prostate, melanoma), cavernous hemangiomas, and plasma cell tumors [23,24]. A history of systemic malignancy, especially involving the head or neck, should be sought and the physical examination should be meticulous for signs of malignancy.…”
Section: Neoplasticmentioning
confidence: 99%