Metastatic rectal gastrointestinal stromal tumor with intestinal obstruction: A rare case report

Kassimi, Mariam; Amal, Rami; Guerroum, Hind; Habi, Jihane; Rahmouni, Imane; Mahi, M.

doi:10.1016/j.radcr.2021.11.003

Cited by 2 publications

(1 citation statement)

References 5 publications

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“…MRI has advantages in diagnosing hepatic metastasis; a previous study reported that MRI detected additional hepatic metastasis, which was not detected via CT [ 38 ]. Additionally, MRI enables detailed visualization of the pelvic anatomy, including the anal sphincter and anal verge, as well as the tumor itself [ 39 ].…”

Section: Imaging Modalitymentioning

confidence: 99%

Gastrointestinal stromal tumors: a comprehensive radiological review

Inoue

Ota²,

Yamasaki

et al. 2022

Jpn J Radiol

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Gastrointestinal stromal tumors (GISTs) originating from the interstitial cells of Cajal in the muscularis propria are the most common mesenchymal tumor of the gastrointestinal tract. Multiple modalities, including computed tomography (CT), magnetic resonance imaging (MRI), fluorodeoxyglucose positron emission tomography, ultrasonography, digital subtraction angiography, and endoscopy, have been performed to evaluate GISTs. CT is most frequently used for diagnosis, staging, surveillance, and response monitoring during molecularly targeted therapy in clinical practice. The diagnosis of GISTs is sometimes challenging because of the diverse imaging findings, such as anatomical location (esophagus, stomach, duodenum, small bowel, colorectum, appendix, and peritoneum), growth pattern, and enhancement pattern as well as the presence of necrosis, calcification, ulceration, early venous return, and metastasis. Imaging findings of GISTs treated with antineoplastic agents are quite different from those of other neoplasms (e.g. adenocarcinomas) because only subtle changes in size are seen even in responsive lesions. Furthermore, the recurrence pattern of GISTs is different from that of other neoplasms. This review discusses the advantages and disadvantages of each imaging modality, describes imaging findings obtained before and after treatment, presents a few cases of complicated GISTs, and discusses recent investigations performed using CT and MRI to predict histological risk grade, gene mutations, and patient outcomes.

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Section: Imaging Modalitymentioning

confidence: 99%

Gastrointestinal stromal tumors: a comprehensive radiological review

Inoue

Ota²,

Yamasaki

et al. 2022

Jpn J Radiol

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Clinical characteristics and prognosis of gastrointestinal stromal tumors with rare site metastasis (Review)

Liang

Kong

2022

Oncol Lett

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Gastrointestinal stromal tumors (GIST) are the most common stromal-derived tumors of the gastrointestinal tract and have a potential metastatic capacity in almost half of all cases, with the most common sites of metastasis being the liver and peritoneum. However, there is evidence that GIST metastasizes to sites other than the liver and peritoneum, which poses challenges for clinical diagnosis and treatment. Therefore, the Cochrane and Medline databases were searched via PubMed in July 2022 using relevant keywords to acquire the literature associated with the metastasis of GIST to rare sites published since from 2000 onwards. Study data comprising age, sex, primary location, metastatic site, mean survival time, clinical signs and symptoms, imaging, pathological features immunohistochemical indices, treatment and prognosis were recorded and analyzed. The 118 metastases at rare sites reported in the literature included bone (n=31), lung (n=10), lymph nodes (n=13), intracranial sites (n=13), skin and subcutaneous tissue (n=10), heart (n=7), skeletal muscle (n=7), orbit and choroid (n=6), pancreas (n=3), spleen (n=2), bone marrow (n=1), testis (n=3), scrotum (n=1), epididymis (n=1), penis (n=1), ovary (n=2), cervix (n=1), kidney (n=1), bladder (n=1), adrenal gland (n=2) and thyroid gland (n=2). From the reviewed studies, it may be concluded that when metastases from gastrointestinal stromal tumors occur at rare sites, the initial symptoms may help in the identification of these sites. In addition, the site-dependent imaging of different metastatic locations may further define the metastases, and the findings of pathological or immunohistochemical analyses may be used to confirm the diagnosis. Contents Introduction 2. Materials and methods3. Rare metastatic sites and basic characteristics of patients 4. Diagnosis of rare site metastasis of GIST 5. Therapy and prognosis for rare site GIST metastases 6.

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Metastatic rectal gastrointestinal stromal tumor with intestinal obstruction: A rare case report

Cited by 2 publications

References 5 publications

Gastrointestinal stromal tumors: a comprehensive radiological review

Gastrointestinal stromal tumors: a comprehensive radiological review

Clinical characteristics and prognosis of gastrointestinal stromal tumors with rare site metastasis (Review)

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