Metastatic Osteoarticular Infective Endocarditis by Methicillin-sensitive Staphylococcus Aureus

Al-Bayati, Asseel; Alshami, Abbas; Al-Azzawi, Mohammed; Al-Hillan, Alsadiq; Hossain, Mohammad A.

doi:10.7759/cureus.8124

Cited by 2 publications

(2 citation statements)

References 17 publications

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“…Staphylococcus aureus is a leading cause of human bacterial infection, and the most common site of Staphylococcus aureus infection is the skin[ 13 ]. Skin and soft tissue infections with Staphylococcus remain a dominant cause of bacteraemia and IE[ 14 , 15 ].…”

Section: Discussionmentioning

confidence: 99%

Staphylococcus aureus bacteremia and infective endocarditis in a patient with epidermolytic hyperkeratosis: A case report

Chen¹,

Chen²,

Líu³

et al. 2022

World J Clin Cases

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BACKGROUND Staphylococcus aureus bacteraemia (SAB) is among the leading causes of bacteraemia and infectious endocarditis. The frequency of infectious endocarditis (IE) among SAB patients ranges from 5% to 10%-12%. In adults, the characteristics of epidermolytic hyperkeratosis (EHK) include hyperkeratosis, erosions, and blisters. Patients with inflammatory skin diseases and some diseases involving the epidermis tend to exhibit a disturbed skin barrier and tend to have poor cell-mediated immunity. CASE SUMMARY We describe a case of SAB and infective endocarditis in a 43-year-old male who presented with fever of unknown origin and skin diseases. After genetic tests, the skin disease was diagnosed as EHK. CONCLUSION A breached skin barrier secondary to EHK, coupled with inadequate sanitation, likely provided the opportunity for bacterial seeding, leading to IE and deep-seated abscess or organ abscess. EHK may be associated with skin infection and multiple risk factors for extracutaneous infections. Patients with EHK should be treated early to minimize their consequences. If patients with EHK present with prolonged fever of unknown origin, IE and organ abscesses should be ruled out, including metastatic spreads.

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Section: Discussionmentioning

confidence: 99%

Staphylococcus aureus bacteremia and infective endocarditis in a patient with epidermolytic hyperkeratosis: A case report

Chen¹,

Chen²,

Líu³

et al. 2022

World J Clin Cases

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show abstract

“…In all described pathologies in the present work, one infection could be the complication of the other which is a pathological behavior frequently observed in S. aureus. In this sense, Albayati et al (2020) have reported that S. aureus skin and soft tissue infections cause an unusual complication of persistent bacteremia which itself leads to complicated endocarditis in addition to an affinity of the involved strain for vertebral osteomyelitis (Al-bayati et al, 2020). Several studies have documented the risk of endocarditis as a complication of bacteremia and have confirmed that it is a serious complication (Bouchiat et al, 2015;Andersen et al, 2020).…”

Section: Invasive Infections Caused By Invasive Infections Caused By ...mentioning

confidence: 99%

From skin infection to invasive diseases: A descriptive review of Staphylococcus aureus, focusing on Panton-Valentine leucocidin and methicillin-resistant strains

ZEOUK¹

2023

Not Sci Biol

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Despite advances in scientific research, Staphylococccus aureus remains a pyogenic and toxigenic bacterium involved in different infections, it endowed with the capacity to infect several biotopes and cause a wide range of infections ranging from skin diseases to other serious pathologies such as pneumonia, meningitis, sepsis, osteomyelitis and infectious endocarditis. Moreover, the emergence of resistant strains constitutes a serious public health problem. Thus, the development of new active compounds from natural sources such as medicinal plants is urgently needed. To this end, the aim of our review was to describe the state of art of infections caused by S. aureus, its pathogenesis, treatment and to provide a synthesis about studies reporting a bio guided isolation of most promising compounds selected for their anti-staphylococcal activity.

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Metastatic Osteoarticular Infective Endocarditis by Methicillin-sensitive Staphylococcus Aureus

Abstract: Al-bayati et al. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 4.0., which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Cited by 2 publications

References 17 publications

Staphylococcus aureus bacteremia and infective endocarditis in a patient with epidermolytic hyperkeratosis: A case report

Staphylococcus aureus bacteremia and infective endocarditis in a patient with epidermolytic hyperkeratosis: A case report

From skin infection to invasive diseases: A descriptive review of Staphylococcus aureus, focusing on Panton-Valentine leucocidin and methicillin-resistant strains

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