1984
DOI: 10.1001/archderm.120.6.768
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Metastasizing eccrine sweat gland carcinoma. Report of a case

Abstract: We report a case of eccrine sweat gland carcinoma arising from the occipital region, which later metastasized to the regional lymph nodes and spread widely to the viscera. After wide local excision of the primary tumor, it recurred locally, and then metastasized presumably via regional lymph nodes. Widespread metastasis to visceral organs occurred after a ten-year latent period from the appearance of the original tumor. Histochemical and enzymatic histochemical examinations of the specimens from the original t… Show more

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Cited by 12 publications
(4 citation statements)
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“…Chemotherapy with methotrexate, cisplatin, adriamycin and bleomycin or isotretinoin and interferon alpha have been used with partial or little response. Radiation therapy and chemotherapy seem to be ineffective to control tumor recurrence or metastasis [16]. In our case, post-op chemotherapy or radiation was not given to the patient.…”
Section: Discussionmentioning
confidence: 91%
See 1 more Smart Citation
“…Chemotherapy with methotrexate, cisplatin, adriamycin and bleomycin or isotretinoin and interferon alpha have been used with partial or little response. Radiation therapy and chemotherapy seem to be ineffective to control tumor recurrence or metastasis [16]. In our case, post-op chemotherapy or radiation was not given to the patient.…”
Section: Discussionmentioning
confidence: 91%
“…Approximately 50% of EPC appear first in the lower limbs; in that, more than 40% occur below the knees [15]. Less than 5% involve the scalp [16]. Other affected sites are face, ear, eyelids, abdomen, vulva, penis and pubis.…”
Section: Discussionmentioning
confidence: 99%
“…Both single-agent and combination chemotherapy have been used infrequently and, at best, have shown only a temporary benefit. [23][24][25][26][27] There have been a few reports in which patients with SEC were treated with radiotherapy for local control and bone metastases; 4,8 however, there have been no previous reports of SEC treated with chemotherapy. The tumor in our patient had already spread to the lungs, inguinal and paraaortic lymph nodes, and bones at the time of initial diagnosis.…”
Section: Discussionmentioning
confidence: 99%
“…The role of chemotherapy in sweat gland carcinoma is also under debate. Both single‐agent and combination chemotherapy have been used infrequently and, at best, have shown only a temporary benefit 23–27 . There have been a few reports in which patients with SEC were treated with radiotherapy for local control and bone metastases; 4,8 however, there have been no previous reports of SEC treated with chemotherapy.…”
Section: Discussionmentioning
confidence: 99%