References1 Wade TR, Kopf AW, Ackerman AB. Bowenoid papulosis of the genitalia. Arch Dermatol 1979; 115:306-8. 2 Kreuter A, Brockmeyer NH, Hochdorfer B et al. Clinical spectrum and virologic characteristics of anal intraepithelial neoplasia in HIV infection. J Am Acad Dermatol 2005; 52:603-8. 3 Weissenborn SJ, Funke AM, Hellmich M et al. Oncogenic human papillomavirus DNA loads in human immunodeficiency virus-positive women with high-grade cervical lesions are strongly elevated. J Clin Microbiol 2003; 41:2763-7. 4 Patterson JW, Kao GF, Graham JH, Helwig EB. Bowenoid papulosis: a clinicopathologic study with ultrastrucural observations. Cancer 1986; 57:823-36. 5 Yoneta A, Yamashita T, Jin HY et al. Development of squamous cell carcinoma by two high-risk human papillomaviruses (HPVs), a novel HPV-67 and HPV-31 from bowenoid papulosis. Br J Dermatol 2000; 143:604-8. 6 Hama N, Ohtsuka T, Yamazaki S. Elevated amount of human papillomavirus 31 DNA in a squamous cell carcinoma developed from bowenoid papulosis. Dermatology 2004; 209:329-32. 7 Sano T, Oyama T, Kashiwabara K et al. Expression status of p16 protein is associated with human papillomavirus oncogenic potential in cervical and genital lesions. Am J Pathol 1998; 153: 1741-8. 8 Snijders PJ, Hogewoning CJ, Hesselink AT et al. Determination of viral load thresholds in cervical scrapings to rule out CIN 3 in HPV 16, 18, 31 and 33-positive women with normal cytology. Int J Cancer 2006; 119:1102-7. 9 Jacobs MV, Snijders PJ, van den Brule AJ et al. A general primer GP5+/GP6(+)-mediated PCR-enzyme immunoassay method for rapid detection of 14 high-risk and 6 low-risk human papillomavirus genotypes in cervical scrapings. J Clin Microbiol 1997; 35: 791-5. 10 van den Brule AJ, Pol R, Fransen-Daalmeijer N et al. GP5+/6+ PCR followed by reverse line blot analysis enables rapid and highthroughput identification of human papillomavirus genotypes. SIR, The inflammatory vesicobullous first stage of incontinentia pigmenti (IP) can recur, albeit rarely. It has previously been described only in infants and young children under the age of 18 months and it has usually been preceded by a systemic infection.A 5-year-old schoolgirl presented with a 2-day history of a linear rash on her right leg extending from the medial knee to the buttock and consisting of vesicobullous lesions arising on inflamed skin (Fig. 1). There was no history of anteceding