Metástase de seminoma em região orbital em cão - relato de caso

Dias, Sanyra Lopes; Moroz, Ludmila Rodrigues; Souza, Diogo Figueiredo; Simões, Lino; Peixoto, Tiago da Cunha; Pires, Cidália

doi:10.1590/1678-4162-10179

Cited by 3 publications

(6 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Both testicles were presented in adequate topography, thus, there was no cryptorchidism, a factor that commonly leads to testicle neoplasms development [1][2]. Recent reports of seminoma in non-cryptorchid animals described mixed testicular neoplasms and/or metastases [4][5][6], which was not the case for this animal.…”

Section: Discussionmentioning

confidence: 99%

“…Only one report in literature describes a non-metastatic and unmixed seminoma in a non-ectopic testis, identified due to testicular enlargement [11], one of the first characteristic symptoms of these neoplasms. However, the case reported in this essay is the first to describe a benign isolated seminoma in an asymptomatic animal, as is most frequent in dogs [2].…”

Section: Discussionmentioning

confidence: 99%

“…In addition to absent of clinical signs, hematological and biochemical laboratory tests and chest radiography also presented no alterations. Normality of these exams has been described in other case of isolated seminoma in nonectopic testes [11]. In general, such exams demonstrate changes in cases of metastases or paraneoplastic syndromes, having great importance for clinical and prognostic evaluation in cases of malignancy [2].…”

Section: Discussionmentioning

confidence: 99%

“…The malignancy incidence of this tumor is between 5% and 10% [1,3]. Cases of metastases have been described in spermatic cord, rede testis, sublumbar lymph nodes, abdominal and thoracic viscera, skin, bone, soft palate, base of the tongue, lip, eye and brain [4][5][6][7][8].…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Testicular seminoma in a dog and its clinical, ultrasonographic, cytological and histopathological aspects: case report

Andrade

Vasconcelos

Colares

et al. 2021

BJCR

View full text Add to dashboard Cite

Neoplasms are amongst the main death causes in dogs, with the testis as the second most affected tissue in non-neutered male dogs and seminoma as one of the most common type. In this study, a 12-years-old non-neutered male teckel dog was attended with no perceived clinic. The ultrasound examination revealed a hypoechogenic nodule of ellipsoid shape and slightly heterogeneous echotexture in right testis. The animal was referred for bilateral orchiectomy and histopathological evaluation confirmed the presence of diffuse seminoma in the right testicle and testicular degeneration in both testes. Prognostic factors evaluated in histopathology designated resolution with orchiectomy.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Testicular seminoma in a dog and its clinical, ultrasonographic, cytological and histopathological aspects: case report

Andrade

Vasconcelos

Colares

et al. 2021

BJCR

View full text Add to dashboard Cite

show abstract

“…Com posse do histórico, sinais clínicos, exame citológico e de imagem, pode-se inferir que esses dados são consistentes com quadro de TVT [11]. Nas apresentações extragenitais, os órgãos mais acometidos são linfonodos inguinais e sublombares, pulmões e diversos órgãos abdominais [7], já os quadros de metástase representam apenas 5% dos casos desta enfermidade [18].…”

Section: Discussionunclassified

Nasal Transmissible Venereal Tumor (TVT) with Bone Metastasis in a Dog

Silva

Marinho

Fonseca

et al. 2022

Acta Scientiae. Vet.

View full text Add to dashboard Cite

Background: Transmissible venereal tumor (TVT) is a highly contagious round cell neoplasm that affects dogs, and it is usually transmitted through coitus. The tumor is mainly located in the genital area; however, the neoplasm can also be extragenital, affecting the nose, mouth, and eyes, as well as the skin and superficial lymph nodes. Cytological examination is the most commonly used method for definitive diagnosis due to its low cost and fast execution. Chemotherapy, radiotherapy, surgical resection, and other procedures such as cryosurgery are the possible treatment options. The objective of this report was to describe a case of extragenital TVT with nasal primary site and metastasis in the bone tissue in a dog treated at a private veterinary hospital in the city of Belém, Pará, Brazil.Case: A 6-year-old male domiciliary Labrador Retriever dog, weighing 24.2 kg, received oncologic treatment in a private veterinary hospital in the city of Belém, Pará, Brazil. The animal had a history of neoplastic disease, and he had undergone TVT resection associated with chemotherapy treatment more than 3 years ago. The clinical examination revealed a volume increase in the periorbital region, left lateral ocular displacement, left nostril excessive epistaxis, recurrent sneezing, cough, and pain signs, and tumor metastasis was suspected. Complementary exams of oncological cytology, computed tomography (CT), hemogram, and serum biochemistry were requested for diagnosis and staging of the condition, and supportive therapy was prescribed. The cytological report showed a dense population of neoplastic round cells with characteristics of TVT. CT indicated the presence of a heterogeneous hypodense mass with irregular contours and partially defined limits, with slight uptake of the intravenously injected contrast medium that obliterated the nasal cavity, maxillary recess, nasopharyngeal meatus, frontal sinus, and sphenoid sinus on the left side. The hematological analysis revealed mild anemia, neutrophilia, and lymphopenia, while the biochemical analysis only showed hypocalcemia. The prescribed therapy was amoxicillin + potassium clavulanate, omega-3, firocoxib, tranexamic acid, and finally chemotherapy with lomustine. Since the patient did not return for follow-up, the outcome could not be determined.Discussion: The patient described in this report was a domiciliary dog who did not live with other pets, but had access to the community environment and contact with other animals. The animal’s history, clinical signs, and cytological and imaging findings were consistent with those of TVT. In extragenital presentations of TVT, the inguinal and sublumbar lymph nodes, lungs, and abdominal organs are most commonly affected. Furthermore, bone involvement is rare, as this has not been commonly described in the literature as compared to the other sites of metastases. An abrasive brush was used for the cytological sample collection, because it provides slides with richer cells as compared to the imprint samples. CT is an important tool for the diagnosis of neoformations in the skeleton, and this method demonstrated high efficiency in identifying the bone involvement and the degree of the invasion and lesion in this case. The therapeutic agents used in this case were different from the usual, since the patient was given lomustine (40 mg/capsule, orally) in the metronomic chemotherapy. This drug has been previously used as an alternative in a canine TVT case resistant to vincristine.Keywords: neoplasm, extragenital, computed tomography, TVT.Título: Tumor Venéreo Transmissível (TVT) nasal com metástase óssea em um cãoDescritores: neoplasia, extragenital, tomografia computadorizada, TVT.

show abstract