Metallic and metal oxide-derived nanohybrid as a tool for biomedical applications

Mujahid, Mohd Hasan; Upadhyay, Tarun Kumar; Khan, Fahad; Pandey, Pratibha; Park, Moon Nyeo; Sharangi, Amit Baran; Upadhye, Vijay; Kim, Bonglee

doi:10.1016/j.biopha.2022.113791

Cited by 42 publications

(14 citation statements)

References 244 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Herein, chemical co-precipitation method was utilized to prepare Alq 3 and Alq 3 /CNTs at very low temperatures. It is easy to control dopant concentrations, chemical composition, shape, and particle size of the hybrid composite using the current technique [11,12]. The findings confirmed that the hybrid Alq 3 /CNTs/p-Si diode of higher efficiency compared with Alq 3 /p-Si diode thanks to the seamless structure and high dispersion capability of CNTs.…”

Section: Introductionsupporting

confidence: 56%

Synthesis of Alq₃ by a facile co-precipitation approach and study the impact of CNTs support on its microstructure and electronic characteristics for photodiode development

Siddiq

2023

Mater. Res. Express

View full text Add to dashboard Cite

The global demand for renewable energy as an alternative to traditional fossil fuels has motivated the scientific community to develop highly efficient nanocomposite materials that can be used for enhancement to optoelectronic technology. In the present work, organometallics Alq3 and Alq3/CNTs were prepared by cost-effective chemical route. X-ray diffraction (XRD) and scanning electron microscopy (SEM) were performed to identify the structural and morphological features. The hybrid Alq3/CNTs exhibited polycrystalline structure with a large surface area. The optical band gap (E_g) of Alq3 film was evaluated within the visible spectrum in the range of 3.047 eV which reduced to 2.979 eV by CNTs integration. Ag/Alq3/p-Si/Al and Ag/Alq3/CNTs/p-Si/Al photodiodes were fabricated using thermal evaporating technique. Current-voltage (I-V) and capacitance/conductance-voltage (C/G-V) were measured to analyze the photodiode behavior. The main electronic parameters like R_s,n,ϕ_b 〖and I〗_o were determined using different models indicating that the composite photodiode of high performance in which R_s was decreased whereas N_a was increased with doping. Besides, the photocurrent sensitivity was increased from 1.45×〖10〗^(-8) A to 1.1 ×〖10〗^(-5) A due to increase of free charge carriers.

show abstract

Section: Introductionsupporting

confidence: 56%

Synthesis of Alq₃ by a facile co-precipitation approach and study the impact of CNTs support on its microstructure and electronic characteristics for photodiode development

Siddiq

2023

Mater. Res. Express

View full text Add to dashboard Cite

show abstract

“…[48] The biological safety and increased antimicrobial activity of metal oxide nanotechnology make them a promising tool in this area. [49] Bacterial cells may be destroyed when the positively charged ions in metal oxides Cu 2 + and Zn 2 + interact with the negatively charged ions on the cell wall. As a result of this, microbes form pits or openings in their cells that could be associated with introduced particles.…”

Section: Analysis Of Anti-microbial Activity Of C Z-1 Z-2 Z-3 and Z-4...mentioning

confidence: 99%

Effect of Zn Doping on Antibacterial Efficacy of CuO Nanostructures

Bhosale,

Moyo

et al. 2023

ChemistrySelect

View full text Add to dashboard Cite

Bacterial diseases are causing major health issues across the world. Recent research has revealed that the metal ion discharge of nanomaterials is extremely effective at eradicating bacterial outbreaks and resistance. Reactive oxygen species (ROS) for antibacterial functions have been produced using nanomaterials with high specific surface area, complex structural framework, and spectral properties. In this study, we thoroughly investigated the impact of Zn dopants on copper oxide (CuO) nanostructures and their nanomaterial‐based antibacterial processes. The method of production includes the formation of CuO and Zn‐doped CuO nanostructures via chemical coprecipitation. By using several characterization techniques, the as‐synthesized nanostructures were confirmed. Based on their specific surface area and surface‐active site, the different antibacterial activities of these dopants vary the antibacterial action. The antibacterial activity was evaluated using the agar well diffusion method. A significant antibacterial action was observed in the samples. In the pharmaceutical and food sectors, this CuO and its combined dopants can be a substitute for synthetic antibacterial agents.

show abstract

“…The multiple properties of nanoparticles (NPs), including smaller size, high surface-to-volume ratio, unique fluorescent features, increased permeability, and remarkable biocompatibility, offer several advantages in cancer treatment [ 10 ]. Among the nanoparticles, metallic NPs have great potential to be utilized as pharmacological agents and exhibit a superior performance compared to other NPs [ 11 ]. Owing to their unique optical, electrical, magnetic, and catalytic capabilities, which are typically different from those of their monometallic counterparts, bimetallic NPs have drawn much attention in the last decade.…”

Section: Introductionmentioning

confidence: 99%

Biogenic Synthesis of Cu-Mn Bimetallic Nanoparticles Using Pumpkin Seeds Extract and Their Characterization and Anticancer Efficacy

et al. 2023

View full text Add to dashboard Cite

Background: Cancer is a chronic, heterogeneous illness that progresses through a spectrum of devastating clinical manifestations and remains the 2nd leading contributor to global mortality. Current cancer therapeutics display various drawbacks that result in inefficient management. The present study is intended to evaluate the anticancer potential of Cu-Mn bimetallic NPs (CMBNPs) synthesized from pumpkin seed extract against colon adenocarcinoma cancer cell line (HT-29). Methods: The CMBNPs were biosynthesized by continuously stirring an aqueous solution of pumpkin seed extract with CuSO4 and manganese (II) acetate tetrahydrate until a dark green solution was obtained. The characteristic features of biogenic CMBNPs were assessed by UV-visible spectrophotometry (UV-vis), X-ray powder diffraction (XRD), energy-dispersive X-ray (EDX), scanning electron microscopy (SEM), and transmission electron microscopy (TEM). A battery of biological assays, viz. neutral red uptake (NRU) assay, in vitro scratch assay, and comet assay, were performed for anticancer efficacy evaluation. Results: The formation of spherical monodispersed bimetallic nanoparticles with an average size of 50 nm was recorded using TEM. We observed dose-dependent cytotoxicity of CMBNPs in the HT-29 cell line with an IC50 dose of 115.2 µg/mL. On the other hand, CMBNPs did not show significant cytotoxicity against normal cell lines (Vero cells). Furthermore, the treatment of CMBNPs inhibited the migration of cancer cells and caused DNA damage with a significant increase in comet tail length. Conclusions: The results showed substantial anticancer efficacy of CMBNPs against the studied cancer cell line. However, it is advocated that the current work be expanded to different in vitro cancer models so that an in vivo validation could be carried out in the most appropriate cancer model.

show abstract

Metallic and metal oxide-derived nanohybrid as a tool for biomedical applications

Cited by 42 publications

References 244 publications

Synthesis of Alq₃ by a facile co-precipitation approach and study the impact of CNTs support on its microstructure and electronic characteristics for photodiode development

Synthesis of Alq₃ by a facile co-precipitation approach and study the impact of CNTs support on its microstructure and electronic characteristics for photodiode development

Effect of Zn Doping on Antibacterial Efficacy of CuO Nanostructures

Biogenic Synthesis of Cu-Mn Bimetallic Nanoparticles Using Pumpkin Seeds Extract and Their Characterization and Anticancer Efficacy

Contact Info

Product

Resources

About

Metallic and metal oxide-derived nanohybrid as a tool for biomedical applications

Cited by 42 publications

References 244 publications

Synthesis of Alq3 by a facile co-precipitation approach and study the impact of CNTs support on its microstructure and electronic characteristics for photodiode development

Synthesis of Alq3 by a facile co-precipitation approach and study the impact of CNTs support on its microstructure and electronic characteristics for photodiode development

Effect of Zn Doping on Antibacterial Efficacy of CuO Nanostructures

Biogenic Synthesis of Cu-Mn Bimetallic Nanoparticles Using Pumpkin Seeds Extract and Their Characterization and Anticancer Efficacy

Contact Info

Product

Resources

About

Synthesis of Alq₃ by a facile co-precipitation approach and study the impact of CNTs support on its microstructure and electronic characteristics for photodiode development

Synthesis of Alq₃ by a facile co-precipitation approach and study the impact of CNTs support on its microstructure and electronic characteristics for photodiode development