On the basis of the recently proposed self-consistent theory of metal-insulator transition in strongly disordered systems, taking into account interaction effects, we study transition temperature T c suppression in disordered superconductors for the wide disorder interval -from weakly disordered metal up to Anderson insulator, induced by "Coulomb pseudogap" formation in the density of states. It is shown that for a number of systems this theory provides rather satisfactory fit of experimental data. PACS numbers: 71.30+h, 71.55.Jv, 72.15Rn, 74.20.Fg Typeset using REVT E X 1 The problem of degradation of superconducting transition temperature under strong disordering is relatively old [1]. It is closely connected with the question of superconductivity suppression due to disorder-induced metal-insulator transition [2]. A number of microscopic mechanisms of T c suppression were proposed, such as the growth of Coulomb pseudopotential [3,4], the influence of Coulomb corrections to the density of states [5] etc. In the majority of papers only small corrections to T c due to these effects were analyzed.Recently we proposed [6,7] a theory of metal-insulator transitions which generalize the self-consistent theory of localization [8,9] taking into account the effects of electron-electron interaction. This approach has allowed us to study the behavior of the generalized diffusion coefficient for the wide interval of disorder parameter both for metallic and insulating regions.These results were used in calculations of one-particle density of states with the account of interelectron interactions. These calculations demonstrate the formation and the growth of the "Coulomb pseudogap" in the density of states close to the Fermi level. In metallic region this behavior of the density of states corresponds to the usual square-root Altshuler-Aronov correction [10]. As disorder parameter grows and system moves towards the metalinsulator transition this pseudogap deepens, while the effective region of square-root behavior diminishes, and at the point of the metal-insulator transition the density of states at the Fermi level becomes equal to zero -we obtain a kind of a "Coulomb gap". In the insulating region, for the band of the finite width, we obtain the typical quadratic behavior of the density of states close to the Fermi level, reminiscent of the Coulomb gap due to Efros and Shklovskii [11], widening with the further growth of disorder. Such behavior of the density of states is in qualitative agreement with experiments on the number of disordered systems close to the metal-insulator transition [1], from amorphous alloys [12,13,15,16] to disordered single-crystals of metallic oxides, including high-temperature superconductors [17]. In this paper the results of these calculations of the density of states are used for the numerical study of "Coulomb gap" effects on the T c suppression for superconductors which are close to the metal-insulator transition.We shall analyze superconductivity within the framework of the simplest BCS-model....