Metal-Containing Poly(ionic liquid) Membranes for Antibacterial Applications

Abstract

Imidazolium-type metal-containing ionic liquid (IL) monomers and their corresponding poly(ionic liquid) (PIL) membranes coordinated with CuCl 2 (PILM-Cu), FeCl 3 (PILM-Fe), or ZnCl 2 (PILM-Zn) were synthesized. The effect of metal ions on the antimicrobial activities against both Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli) was investigated. Compared with pristine PILM-Br membrane, PILM-Cu, PILM-Fe, and PILM-Zn membranes exhibit enhanced antibacterial activities due to the attributes of both imidazolium cations and metal-containing anions. Furthermore, all of the metal-containing PIL membranes present low hemolysis toward human red blood cell and high long-term antibacterial stability, even after immersion in water for 90 days, demonstrating clinical feasibility in topical applications.

Poly(ionic liquid) composites

“…The presence of metal ions generated reactive oxygen species (ROS), such as singlet oxygen ( 1 O 2 ), that progressively oxidized the bacterial cell wall. 60 Yang and coworkers immobilized Cr 3+ ions onto a SO 3 H-functionalized solid PIL via coordination interactions. Simultaneous functionalization with Brønsted/Lewis acidic groups in such heterogeneous catalysts enhanced catalytic activity.…”

Metal‐containing Ionic Liquid/Polyacrylonitrile‐derived Carbon Nanofibers for Oxygen Reduction Reaction and Flexible Zn–Air Battery

“…The synthetic procedure of porous Fe‐ N ‐codoped ECNFs are schematically illustrated in Figure . The synthesis of tetrabutylammonium bromotrichloroferrate (IL‐Fe) was modified via referring to the previous literature . Polyacrylonitrile (PAN)/IL‐Fe/DMF solution underwent electrospinning to form carbon precursors.…”

The synthesis and application of poly(ionic liquid)s functional materials

“…研究结果表明, 不同氨基酸阴离子对 44 抗菌性能影响显著 [86,87] ，同时该团队还制备了含金属 45 阴离子(CuCl2Br − , FeCl3Br − , ZnCl2Br − )的聚离子液体抗 46 菌膜(图 15). 研究表明含金属阴离子的引入可以显著 47 提高聚离子液体薄膜的抗菌性能 [88] . 48…”