2019
DOI: 10.1080/15287394.2019.1566105
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Abstract: Iron (Fe) deficiency (FeD) and manganese (Mn) overexposure (MnOE) may result in several neurological alterations in the nervous system. Iron deficiency produces unique neurological deficits due to this elemental role in central nervous system (CNS) development and myelination, which might persist after normalization of Fe in the diet. Conversely, MnOE, is associated with diverse neurocognitive deficits. Despite these well-known neurotoxic effects on the CNS, the influence of FeD and MnOE on the peripheral nerv… Show more

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Cited by 6 publications
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“…The effects of IDA on peripheral motor nerve function has been investigated in human patients: this cross-sectional study revealed a functional impairment of peripheral nerves in condition of iron deficiency in terms of prolonged distal motor latency, reduced amplitude of compound muscle action potential, and reduced motor nerve conduction velocity [191]. Amos-Kroohs et al [192] evaluated the effect of iron deficiency on rats' peripheral nerves. They showed that iron deficiency caused a decrease in MBP and PMP22 expression, interfering with peripheral myelination.…”
Section: Ironmentioning
confidence: 99%
“…The effects of IDA on peripheral motor nerve function has been investigated in human patients: this cross-sectional study revealed a functional impairment of peripheral nerves in condition of iron deficiency in terms of prolonged distal motor latency, reduced amplitude of compound muscle action potential, and reduced motor nerve conduction velocity [191]. Amos-Kroohs et al [192] evaluated the effect of iron deficiency on rats' peripheral nerves. They showed that iron deficiency caused a decrease in MBP and PMP22 expression, interfering with peripheral myelination.…”
Section: Ironmentioning
confidence: 99%