Metabolites of endophytic fungi as novel source of biofungicide: a review

Kumar, Susheel; Kaushik, Nutan

doi:10.1007/s11101-013-9271-y

Cited by 64 publications

(39 citation statements)

References 52 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…There are many reports of metabolites with antifungal and antioomycete activity from endophytic fungi, but there are few studies that explore the herbicidal and antimicrobial activity of the volatile and semi‐volatile compounds from endophytes (Kumar and Kaushik ; Guzmán‐Trampe et al . ).…”

Section: Introductionmentioning

confidence: 99%

Phytotoxic and antimicrobial activity of volatile and semi-volatile organic compounds from the endophyteHypoxylon anthochroumstrain Blaci isolated fromBursera lancifolia(Burseraceae)

et al. 2016

View full text Add to dashboard Cite

show abstract

Section: Introductionmentioning

confidence: 99%

Phytotoxic and antimicrobial activity of volatile and semi-volatile organic compounds from the endophyteHypoxylon anthochroumstrain Blaci isolated fromBursera lancifolia(Burseraceae)

et al. 2016

View full text Add to dashboard Cite

show abstract

“…Gas chromatography‐flame‐ionization detection (GC‐FID) analysis of all of these extracts confirmed the presence of a mixture of fatty acids ( Table ). The genera Colletotrichum , Fusarium , Nigrospora , and Diaporthe include species described as endophytic associated with different plants and capable to produce bioactive compounds . Fractions 1 – 10 obtained from the fractionation of Diaporthe cuppatea EPU 24CA extract were submitted to antifungal assay and fractions 9 and 10 displayed activity.…”

Section: Resultsmentioning

confidence: 99%

Molecular Phylogeny, Diversity, and Bioprospecting of Endophytic Fungi Associated with wild Ethnomedicinal North American Plant Echinacea purpurea (Asteraceae)

Carvalho

Wedge

Cantrell

et al. 2016

Chemistry & Biodiversity

View full text Add to dashboard Cite

The endophytic fungal community associated with the ethnomedicinal plant Echinacea purpurea was investigated as well as its potential for providing antifungal compounds against plant pathogenic fungi. A total of 233 endophytic fungal isolates were obtained and classified into 42 different taxa of 16 genera, of which Alternaria alternata, Colletotrichum dematium, and Stagonosporopsis sp. 2 are the most frequent colonizers. The extracts of 29 endophytic fungi displayed activities against important phytopathogenic fungi. Eight antifungal extracts were selected for chemical analysis. Forty fatty acids were identified by gas chromatography-flame-ionization detection (GC-FID) analysis. The compounds (-)-5-methylmellein and (-)-(3R)-8-hydroxy-6-methoxy-3,5-dimethyl-3,4-dihydroisocoumarin were isolated from Biscogniauxia mediterraneaEPU38CA crude extract. (-)-5-Methylmellein showed weak activity against Phomopsis obscurans, P. viticola, and Fusarium oxysporum, and caused growth stimulation of C. fragariae, C. acutatum, C. gloeosporioides, and Botrytis cinerea. (-)-(3R)-8-Hydroxy-6-methoxy-3,5-dimethyl-3,4-dihydroisocoumarin appeared slightly more active in the microtiter environment than 5-methylmellein. Our results indicate that E. purpurea lives symbiotically with different endophytic fungi, which are able to produce bioactive fatty acids and aromatic compounds active against important phytopathogenic fungi. The detection of the different fatty acids and aromatic compounds produced by the endophytic community associated with wild E. purpurea suggests that it may have intrinsic mutualistic resistance against phytopathogen attacks in its natural environment.

show abstract

“…8.5), a novel compound with an unknown quinolactacide-isochroman skeleton, was isolated from rice cultures of Penicillium citri- num, an endophytic fungus from Ceratonia siliqua. Compound 325 showed cytotoxicity against L5178Y cells (IC 50 6.1 μM) comparable with the positive control kahalalide F (IC 50 4.3 μM). In the antibacterial assays, it was not active against S. aureus ATCC 29213, S. pneumoniae ATCC 49619, and E. coli ATCC 25922 at the concentration of 64 μg/mL [91].…”

Section: Fig 82 (Continued)mentioning

confidence: 86%

“…There are many specialized reviews covering the biological activities of the new compounds that have been isolated from endophytic and associated marine derived fungi [2,3,6,15,22,23,[40][41][42][43][44][45][46][47][48][49][50].…”

Section: Xylaria Plebejamentioning

confidence: 99%