Metabolism of the Alloxan Diabetic Rat Retina

Inner Retinal Oxygen Delivery and Metabolism in Streptozotocin Diabetic Rats

“…Inner retinal oxygen metabolism measurements were similar among STZ and healthy control rats in the current study. Oxygen metabolism measurements of whole retinas removed from alloxan-induced diabetic rats were higher than in healthy control retinas, 60 though glucose metabolism measurements in STZ rats were not elevated by hyperglycemia. 61 Although outer retina oxygen consumption of long-term diabetic cats has been reported, 62 it is difficult to compare these results to our findings of inner retina oxygen consumption of short-term diabetic rats because of differences in species, duration of diabetes, and retinal cell layers.…”

Inner Retinal Oxygen Delivery and Metabolism in Streptozotocin Diabetic Rats

“…Inner retinal oxygen metabolism measurements were similar among STZ and healthy control rats in the current study. Oxygen metabolism measurements of whole retinas removed from alloxan-induced diabetic rats were higher than in healthy control retinas, 60 though glucose metabolism measurements in STZ rats were not elevated by hyperglycemia. 61 Although outer retina oxygen consumption of long-term diabetic cats has been reported, 62 it is difficult to compare these results to our findings of inner retina oxygen consumption of short-term diabetic rats because of differences in species, duration of diabetes, and retinal cell layers.…”

The retinal blood flow in diabetes

“…If diabetic retinae required increased amounts of oxygen as indicated by some workers [21,22] the stimulus would be even greater. This hypothesis though probably too simple is also attractive because it explains the poor response of retinal vessels of diabetic patients to changes in blood gases [23].…”

Inner Retinal Oxygen Delivery, Metabolism, and Extraction Fraction in Ins2Akita Diabetic Mice

“…Increased total retinal oxygen consumption in excised alloxan-diabetic rat retinas was reported by de Roetth. 43 …”

Inner Retinal Oxygen Delivery and Metabolism in Streptozotocin Diabetic Rats

“…Inner retinal oxygen metabolism measurements were similar among STZ and healthy control rats in the current study. Oxygen metabolism measurements of whole retinas removed from alloxan-induced diabetic rats were higher than in healthy control retinas, 60 though glucose metabolism measurements in STZ rats were not elevated by hyperglycemia. 61 Although outer retina oxygen consumption of long-term diabetic cats has been reported, 62 it is difficult to compare these results to our findings of inner retina oxygen consumption of short-term diabetic rats because of differences in species, duration of diabetes, and retinal cell layers.…”

The retinal blood flow in diabetes

“…If diabetic retinae required increased amounts of oxygen as indicated by some workers [21,22] the stimulus would be even greater. This hypothesis though probably too simple is also attractive because it explains the poor response of retinal vessels of diabetic patients to changes in blood gases [23].…”

Inner Retinal Oxygen Delivery, Metabolism, and Extraction Fraction in Ins2Akita Diabetic Mice

“…Increased total retinal oxygen consumption in excised alloxan-diabetic rat retinas was reported by de Roetth. 43 …”

Inner Retinal Oxygen Delivery and Metabolism in Streptozotocin Diabetic Rats

“…Inner retinal oxygen metabolism measurements were similar among STZ and healthy control rats in the current study. Oxygen metabolism measurements of whole retinas removed from alloxan-induced diabetic rats were higher than in healthy control retinas, 60 though glucose metabolism measurements in STZ rats were not elevated by hyperglycemia. 61 Although outer retina oxygen consumption of long-term diabetic cats has been reported, 62 it is difficult to compare these results to our findings of inner retina oxygen consumption of short-term diabetic rats because of differences in species, duration of diabetes, and retinal cell layers.…”

The retinal blood flow in diabetes

“…If diabetic retinae required increased amounts of oxygen as indicated by some workers [21,22] the stimulus would be even greater. This hypothesis though probably too simple is also attractive because it explains the poor response of retinal vessels of diabetic patients to changes in blood gases [23].…”

Inner Retinal Oxygen Delivery, Metabolism, and Extraction Fraction in Ins2Akita Diabetic Mice

“…Increased total retinal oxygen consumption in excised alloxan-diabetic rat retinas was reported by de Roetth. 43 …”