Metabolic Syndrome Predisposes to Depressive Symptoms

Koponen, Hannu; Jokelainen, Jari; Keinänen‐Kiukaanniemi, Sirkka; Kumpusalo, Esko; Vanhala, Mauno

doi:10.4088/jcp.v69n0202

Cited by 153 publications

(127 citation statements)

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“…Patients with TRD were older, had longer duration of disease, higher number of both depressive episodes and suicide attempts, as well as increased current suicidality, compared to non TRD patients. MetS was observed in 33.5% of patients which is agreement with the 24-36% prevalence of MetS in patients with depression (Koponen et al 2008;Pannier et al 2006). To the best of our knowledge, this is the first study investigating the association between TRD, MetS and its components.…”

Section: Discussionsupporting

confidence: 84%

“…In general, MetS may be an important predisposing factor for the later development of depression (Koponen et al 2008), or cardiovascular disease (Pannier et al 2006) in healthy subjects, while severe depressive symptoms or extremely stressful life event(s) may predict the risk for later development of the MetS (Raikkonen et al 2007). Furthermore, depressed compared to non-depressed subjects have greater risk of developing MetS, elevated waist circumference and increased glucose levels (Toker et al 2008), while depression scores were significantly higher in healthy subjects with than without MetS (Pannier et al 2006;Skilton et al 2007;Toker et al 2008).…”

Section: Introductionmentioning

confidence: 99%

“…Although a number of studies (Koponen et al 2008;Pannier et al 2006;Richter et al 2010;Zeugmann et al 2010) investigated the link between depression and MetS, and both MetS and treatment resistance are common in MDD patients, the association between MetS and TRD is still not clear (Chokka et al, 2006). The aim of our study was to determine whether MetS, or its components, or other cardiovascular risk factors, are related to treatment resistance in patients with MDD.…”

Section: Introductionmentioning

confidence: 99%

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The lack of association between components of metabolic syndrome and treatment resistance in depression

et al. 2013

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(2013) The lack of association between components of metabolic syndrome and treatment resistance in depression. npivac@irb.hr Psychopharmacology, 230 (1). Conflicts of Interest:Authors declare no conflict of interest. All authors state that they have full control of all primary data and that they agree to allow the journal to review this data. Acknowledgments:This study was supported by the Croatian Ministry of Science, Education and Sport, grants numbers 098-0982522-2455; 098-0982522-2457; 109-1083509-3513; 108-1083509-3511.

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Section: Discussionsupporting

confidence: 84%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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The lack of association between components of metabolic syndrome and treatment resistance in depression

et al. 2013

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“…This finding was also obtained with middle-aged patients with MS and measured by the BDI (Koponen, Jokelainnen, Keinänen-Kiukaanniemi, Kumpusalo & Vanhala, 2007). Other authors, using the reverse approach, found a higher prevalence of MS in women who already had a history of depression (Kinder, Carnethon, Palaviappan, King & Fortmann, 2004).…”

Section: Discussionsupporting

confidence: 68%

Depressive and anxiety symptoms in patients with Metabolic Syndrome

Sharovsky

Romano

2013

Estud. psicol. (Campinas)

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Depressive symptoms have been associated to the Metabolic Syndrome. Nevertheless, only a few studies have evaluated anxiety and depression concomitantly. The objective of the research was to evaluate the intensity of depressive and anxiety symptoms in patients with Metabolic Syndrome and their relation to demographic variables. A unicenter, transversal study was carried out. A social demographic questionnaire was used. Depressive symptoms were measured with Beck Depression Inventory and anxiety symptoms were measured with Hamilton Anxiety Scale Rate. A total of 103 ambulatory patients, 60 of them men, with mean age 55.4 years (±7,6) with a diagnosis of Metabolic Syndrome were included in the study. Anxiety symptoms of very severe intensity were present in 51.5% (n=53) while severe depressive symptoms in only 5.8% (n=6). Anxiety and depressive symptoms were significantly associated. In this sample, anxiety predominated in relation to the depressive symptoms. The anxiety symptoms were more intense in women and that had low level of education.

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“…23) Dyslipidemia may mediate the development of depressive symptoms and increase the risk for depression. 24) …”

Section: Introductionmentioning

confidence: 99%

Dehydroepiandrosterone sulfate level varies nonlinearly with symptom severity in major depressive disorder

Kim¹,

Yi²,

Kim³

2016

European Neuropsychopharmacology

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Metabolic Syndrome Predisposes to Depressive Symptoms

Cited by 153 publications

References 0 publications

The lack of association between components of metabolic syndrome and treatment resistance in depression

The lack of association between components of metabolic syndrome and treatment resistance in depression

Depressive and anxiety symptoms in patients with Metabolic Syndrome

Dehydroepiandrosterone sulfate level varies nonlinearly with symptom severity in major depressive disorder

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