Metabolic engineering and pathway construction for biotechnological production of relevant polyhydroxyalkanoates in microorganisms

Making Green Polymers Even Greener:Towards Sustainable Production of Polyhydroxyalkanoates from Agroindustrial By-Products

“…After the discovery of poly(3-hydroxyoctanoate-co-3-hydroxyhexanoate) in octane-grown Pseudomonas oleovorans (de Smet et al, 1983), the range of different constituents of PHAs expanded rapidly, and ca. 200 different PHA monomers have been identified (Steinbüchel & Lütke-Eversloh, 2003). However, the most commonly applied route for tailoring PHAs is their in situ functionalization by biosynthetically producing side chains with terminal double bonds followed by chemistry (revised in Scholz, 2010).…”

Poly(Lactic Acid) as a Biopolymer-Based Nano-Composite

“…For instance, polyhydroxyalkanoates (PHA) produced by bacteria from biodegradable aliphatic homo or copolyesters with over 150 unlike kinds composed of dissimilar monomers (Steinbüchel and Lütke-Eversloh, 2003). Poly(3-hydroxy butyrate) (PHB) and its copolymers with 3-hydroxyvalerate (PHBHV), 3-hydroxyoctanoate (PHBHO), and 3-hydroxyhexanoate (PHBHHx) units are among the largely employed PHAs (Bluhm et al, 1986;Doi et al, 1988;Noda et al, 2004).…”

Potential Utilization of Pineapple Waste Streams for Polyhydroxyalkanoates (PHAs) Production via Batch Fermentation

“…Typically, PHAs are produced and accumulated as an intracellular granule by prokaryotic microorganisms and plants to store as carbon and energy source (Choi and Lee, 1999;Steinbüchel and Lütke-Eversloh, 2003). The presence of excess carbon source, when other essential nutrients such as nitrogen, phosphorous, or sulfur are limiting, is suitable for PHAs synthesis (Anderson and Dawes, 1990).…”